Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
The structure was elucidated in this paperPublication DOI: 10.1016/0008-6215(88)84120-XJournal NLM ID: 0043535Publisher: Elsevier
Institutions: Max-Planck-Institut für Immunbiologie, D-7800 Freiburg F.R.G., Forschungsinstitut Borstel, D-2061 Borstel F.R.G.
The structure of the capsular K74 antigen of E. coli H702c (O44:K74:H18) was elucidated by determination of the composition, 1H- and 13C-n.m.r. and c.d. spectroscopy, periodate oxidation, and methylation analysis of the polysaccharide and of a trisaccharide obtained by mild acid hydrolysis. The K74 antigen has the repeating unit →3)-β-d-Ribf-(1→2)-β-d-Ribf-(1→6)-β-KDOf-(2→. Of the repeating units, ∼65% are O-acetylated, most probably at C-2 of the 3-linked ribose.
Structure type: polymer chemical repeating unit
Location inside paper: p. 228, structure 11
Compound class: K-antigen
Contained glycoepitopes: IEDB_149136
Methods: 13C NMR, 1H NMR, GLC-MS, GLC, CD
Comments, role: O-deacetylated CPS of E. coli H702c (044:K74:H18)
Related record ID(s): 115460
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GTC:G57198VM, GlycomeDB:
5730
Show glycosyltransferases
NMR conditions: in D2O at 306(C) K
[as TSV]
13C NMR data:
Linkage Residue C1 C2 C3 C4 C5 C6 C7 C8
6,2 bDRibf 108.5 75.2 75.2 82.5 64.0
6 bDRibf 106.5 81.5 70.6 83.9 63.1
bXKdof 175.1 109.0 45.1 72.7 87.6 77.9 71.7 63.1
1H NMR data:
missing...
13C NMR data:
| Linkage | Residue | C1 | C2 | C3 | C4 | C5 | C6 | C7 | C8 |
|---|
| 6,2 | bDRibf | 108.5 | 75.2 | 75.2 | 82.5 | 64.0 | |
| 6 | bDRibf | 106.5 | 81.5 | 70.6 | 83.9 | 63.1 | |
| | bXKdof | 175.1 | 109.0 | 45.1 | 72.7 | 87.6 | 77.9 | 71.7 | 63.1 |
|
There is only one chemically distinct structure:
Found 
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