Taxonomic group: plant / Streptophyta
(Phylum: Streptophyta)
Organ / tissue: leaf
NCBI PubMed ID: 10837985Publication DOI: 10.1016/s0378-8741(99)00169-5Journal NLM ID: 7903310Publisher: Limerick: Elsevier Sequoia
Correspondence: Pieroni A <experiences
netcologne.de>
Institutions: Department of Pharmaceutical Sciences, University of Antwerp (UIA), Antwerp, Belgium, Pharmazeutisches Institut der Rheinischen Friedrich-Wilhelms-Universität Bonn, Bonn, Germany, Dipartimento di Scienza del Suolo e Nutrizione della Pianta, Università degli Studi di Firenze, Firenze, Italy
Polar fractions and flavones isolated from methanolic extracts of the leaves of Ligustrum vulgare and Phillyrea latifolia (Oleaceae), whose popular use as an anti-inflammatory is well-known in Mediterranean historical medicine and ethnobotany, showed significant in vitro complement inhibiting effect on the classical pathway of the complement system. Among the isolated flavonoidic structures, apigenin-7-O-glucoside, apigenin-7-O-rutinoside, luteolin-4'-O-glucoside, luteolin-7-O-glucoside and ligustroflavone presented remarkable activity.
Ligustrum vulgare; Phillyrea latifolia; mediterranean ethnomedicine; flavones; anti-complementary activity
Structure type: monomer
Location inside paper: p. 215, Fig. 1
Trivial name: glucoluteolin, luteolin 7-glucoside
Compound class: saponin glycoside, glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside, flavone glucoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_613439,IEDB_983931,SB_192
Methods: inhibition studies, HPLC, extraction
Biological activity: compound showed a dose-dependent inhibitory effect on the classical pathway (CP) of the complement system
Related record ID(s): 67355, 67356, 67357, 67358, 67360, 67361
NCBI Taxonomy refs (TaxIDs): 13597,
126558Reference(s) to other database(s): CCSD:
50066, CBank-STR:939
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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