Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
NCBI PubMed ID: 9272697Journal NLM ID: 7703966Publisher: Japanese Society For Bacteriology
Correspondence: j45811a
nucc.cc.nagoya-u.ac.jp
Institutions: Biosystems, School of Informatics and Sciences, Nagoya University, Nagoya, Aichi 464-01, Japan, Second Department of Hygienic Chemistry, Tohoku College of Pharmacy, Sendai, Japan, Sendai Research Institute for Mycology, Sendai, Miyagi 981, Japan, and Department of Microbiology and Immunology, Aichi Medical University, Nagakute, Aichi 480-11, Japan.
A monoclonal antibody (mAb) with a unique antigenic specificity against Escherichia coli O9 was produced. The O9a mAb was reactive with a part of the strains in E. coli O9. The O9a mAb did not react with LPS from the E. coli O9 test strain Bi316-42. The distribution of the antigen defined by the O9a mAb in E. coli O9 was consistent with that of E. coli O9a present in E. coli O9 strains. The chemical structure of the repeating unit of the O-specific polysaccharide detected by the mAb was demonstrated to be a mannotetraose by two-dimensional nuclear magnetic resonance spectroscopy. It was confirmed that the mAb recognized E. coli O9a serotype in E. coli O9 serotype strains, suggesting that E. coli O9a serotype might be a dominant strain in E. coli O9.
LPS, serotype, Escherichia, Escherichia coli, antibodies, monoclonal antibodies
Structure type: polymer chemical repeating unit
Location inside paper: p.519
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_115576,IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141830,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_174840,IEDB_241100,IEDB_76933,IEDB_983930,SB_136,SB_196,SB_197,SB_44,SB_67,SB_72
Methods: NMR-2D, NMR
Biological activity: serological studies with monoclonal antibodies
Comments, role: published polymerization frame was shifted for conformity with other records
Related record ID(s): 7401, 101047, 108708, 114960
NCBI Taxonomy refs (TaxIDs): 1010797Reference(s) to other database(s): GTC:G54439QN, GlycomeDB:
25319
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error