Taxonomic group: bacteria / Firmicutes
(Phylum: Firmicutes)
Associated disease: infection due to Streptococcus pneumoniae [ICD11:
XN3PW 
]
The structure was elucidated in this paperNCBI PubMed ID: 9449767Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: pjansson
kfc.ki.se
Institutions: Clinical Research Centre, Analitycal Unit, Karolinska Institute, Huddinge Hospital, Huddinge, Sweden
The structure of the capsular polysaccharide from Streptococcus pneumoniae type 18B has been determined using NMR spectroscopy and methylation analysis as the principal methods. It is concluded that the polysaccharide is composed of pentasaccharide repeating units with a glycerol phosphate substituting the 3-position of the branch point residue. The carbohydrate backbone in type 18B is identical to that in S. pneumoniae type 18F but without the O-acetyl groups present in that type. [formula: see text] In this structure, the absolute configuration of the glycerol phosphate moiety has not been determined but should be D, in analogy with that determined for the capsular polysaccharide from S. pneumoniae type 18A [T. Rundlöf, G. Widmalm, Anal. Biochem., 243 (1996) 228-233].
structural, capsular, polysaccharide, Streptococcus, Streptococcus pneumoniae, capsular polysaccharide, type, elucidation, NMR structure, Pneumococcus
Structure type: polymer chemical repeating unit
Location inside paper: Abstract
Compound class: CPS
Contained glycoepitopes: IEDB_130695,IEDB_136044,IEDB_137472,IEDB_141794,IEDB_142487,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_146668,IEDB_153217,IEDB_190606,IEDB_225177,IEDB_885823,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_6,SB_7,SB_88
Methods: NMR
NCBI Taxonomy refs (TaxIDs): 1313Reference(s) to other database(s): GTC:G47718NK
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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