Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Francisella novicida [ICD11:
XN4ZY 
]
The structure was elucidated in this paperNCBI PubMed ID: 15183739Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: evguenii.vinogradov
nrc-cnrc.gc.ca
Institutions: Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada K1A 0R6
Francisella novicida (U112), a close relative of the highly virulent bacterium F. tularensis, is known to produce a lipopolysaccharide that is significantly different in biological properties from the LPS of F. tularensis. Here we present the results of the structural analysis of the F. novicida LPS core part, which is found to be similar to that of F. tularensis, differing only by one additional α-Glc residue:where R is an O-chain, linked via a β-bacillosamine (2,4-diamino-2,4,6-trideoxyglucose) residue. The lipid part of F. novicida LPS contains no phosphate substituent and apparently has a free reducing end, a feature also noted in F. tularensis LPS.
LPS, core structure, Francisella, Francisella novicida
Structure type: polymer chemical repeating unit ; n=9-15
Location inside paper: p.1647
Trivial name: glucan
Contained glycoepitopes: IEDB_135614,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_241101,IEDB_983931,SB_192
Methods: methylation, NMR-2D, NMR, MS
Comments, role: b-glucan linked to -3)x?Gro(1-P-1)x?Gro, contamination in LPS
Related record ID(s): 9248, 9369, 9370, 9371, 9372, 9373, 9374, 9375, 9376
NCBI Taxonomy refs (TaxIDs): 401614Reference(s) to other database(s): GTC:G26777BZ, GlycomeDB:
863
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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