Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: gastroenteritis [ICD11:
1A40.0 
];
diarrhea [ICD11:
ME05.1 , ICD11:
SA55 ]
The structure was elucidated in this paperNCBI PubMed ID: 30861377Publication DOI: 10.1016/j.carres.2019.02.009Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: B. Mukhopadhyay <mbalaram
iiserkol.ac.in>
Institutions: Sweet Lab, Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, Nadia, 741246, India
Chemical synthesis of the pentasaccharide repeating unit of the O-specific polysaccharide from Aeromonas hydrophilastrain K691 is reported. Synthesis of the pentasaccharide is accomplished by using a common disaccharide in sequence and finally attaching the rare sugar unit. The target structure was made in the form of its 2-aminoethyl glycoside which is essential for further glycconjugate formation. Stereoselective glycosylations were achieved by the activation of thioglycosides in the presence of H2SO4-silica in conjunction with N-iodosuccinimide.
O-specific polysaccharide, 6-dideoxy-d-glucose, 4-amino-4, total synthesis, Fish pathogen, H(2)SO(4)-Silica
Structure type: oligomer
Location inside paper: fig.1, scheme 3, structure 1
Compound class: O-polysaccharide
Contained glycoepitopes: IEDB_120354,IEDB_135813,IEDB_135849,IEDB_136105,IEDB_137340,IEDB_141807,IEDB_151531,IEDB_225177,IEDB_885823
Methods: 13C NMR, 1H NMR, TLC, chemical synthesis, optical rotation measurement, flash chromatography
Synthetic data: chemical
Comments, role: pentasaccharide repeating unit of the OPS from A. hydrophila K691
NCBI Taxonomy refs (TaxIDs): 644
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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