CSDB: Search results

Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Associated disease: cystic fibrosis (CF) [ICD11: CA25

]

NCBI PubMed ID: 33434849
Publication DOI: 10.1016/j.sbi.2020.12.003
Journal NLM ID: 9107784
Publisher: Elsevier
Correspondence: silipo

unina.it
Institutions: Dipartimento di Scienze Chimiche, Complesso Universitario Monte Sant'Angelo, Universita di Napoli Federico II, Via Cintia 4, I-80126 Napoli, Italy

The analysis of the bacterial glycome (glycomics) is among the complex 'omics' analysis owing to the inherent difficulties in structural and functional characterization of glycans. The complexity and variability of bacterial glycans, spanning from simple carbohydrates to complex glycolipids, glycopeptides and glycoproteins, make their study a challenging research area. The last two decades have witnessed tremendous advances and development of highly sophisticated methods, in combination with optimized protocols and hyphenate techniques for the understanding of structure, conformations, dynamics and organization of microbial glycans. We here present an overview of the novel approaches that have massively improved our understanding of the carbohydrate-based world of bacteria.

Bacterial, characterization, glycopolymer, Glycomics, glycome, microbial glycans

Structure type: oligomer
Location inside paper: Fig. 1c
Compound class: LOS
Contained glycoepitopes: IEDB_130650,IEDB_130670,IEDB_135607,IEDB_135609,IEDB_136105,IEDB_136906,IEDB_137472,IEDB_140087,IEDB_140088,IEDB_140090,IEDB_141794,IEDB_141807,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_151528,IEDB_151531,IEDB_176772,IEDB_190606,IEDB_2189047,IEDB_225177,IEDB_226811,IEDB_885823,IEDB_983931,SB_192,SB_7

Comments, role: review

NCBI Taxonomy refs (TaxIDs): 95486
Reference(s) to other database(s): GlycomeDB:34713
Show glycosyltransferases

There is only one chemically distinct structure:

CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCCCC)CC(=O)N[C@H]1[C@H](OC[C@H]2O[C@H](OP(=O)(O)O[C@H]3OC[C@H](N)[C@H](O)[C@H]3O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]2O)O[C@H](CO[C@]2(C(=O)O)C[C@@H](O[C@@]3(C(=O)O)O[C@H]([C@H](O)CO[C@H]4OC[C@H](N)[C@H](O)[C@H]4O)[C@H](O)[C@H](O)[C@@H]3O)[C@@H](O[C@H]3O[C@H]([C@@H](O)CO)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O[C@H]4O[C@H]([C@@H](O)CO[C@H]5O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H](O)[C@H](O[C@H]5O[C@H](CO[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H](O)[C@H](O)[C@H]5O[C@H]5O[C@H]([C@@H](O)CO[C@@H]6O[C@H](C)[C@@H](O)[C@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H]6NC(C)=O)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H]4O)[C@@H]3O)[C@@H]([C@H](O)CO)O2)[C@@H](OP(=O)(O)O)[C@@H]1OC(=O)C[C@H](O)CCCCCCCCCCC

SVG MW SMILES 3D mol Ionize