Saponins were isolated from roots of Bupleurum marginatum (Zhuye-Chaihu), B. marginatum var. stenophyllum (Zezhuye-Chaihu) and B. rockii (Lijiang-Chaihu) collected in Yunnan, China, and identified. For the evaluation of these plants as a medicine, quantitative analysis of pharmacologically active saponins, saikosaponins-a (1) and -d (3), in the plants was also conducted in comparison with B. falcatum and B. chinensis.

saikosaponin, Umbelliferae, Chinese Bupleuri radix, Saiko, Chaihu, Bupleurum marginatum, B. marginatum var. stenophyllum, Bupleurum rockii, Yunnan medicinal plant, acetylsaikosaponin

• Compound ID: 23791
  

  b-D-Glcp-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin F = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: saikosaponin a, saikosaponin-a
  Compound class: saponin glycoside, glycoside, triterpenoid glycoside
  Reference(s) to other database(s): CCSD:27760, CBank-STR:3093
  
   
  
  Bupleurum marginatum var. stenophyllum, Bupleurum marginatum, Bupleurum rockii
  CSDB ID 119365 (all data & tools)
• Compound ID: 23792
  

  b-D-Glcp-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin G = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: saikosaponin d, saikosaponin-d
  Compound class: saponin glycoside, glycoside, triterpenoid glycoside
  Reference(s) to other database(s): CCSD:933, CBank-STR:5893
  
   
  
  Bupleurum marginatum var. stenophyllum, Bupleurum rockii
  CSDB ID 119367 (all data & tools)
• Compound ID: 23793
  

  b-D-Glcp-(1-6)-+ | a-L-Rhap-(1-4)-b-D-Glcp-(1-3)-Subst Subst = saikogenin E = SMILES CC1(C){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: saikosaponin c, saikosaponin-c
  Compound class: saponin glycoside, glycoside, triterpenoid glycoside
  Reference(s) to other database(s): CCSD:22000, CBank-STR:7058, Chemspider:146896
  
   
  
  Bupleurum rockii, Bupleurum marginatum, Bupleurum marginatum var. stenophyllum
  CSDB ID 119366 (all data & tools)
• Compound ID: 24417
  

  b-D-Xylp-(1-2)-b-D-Glcp-(1-3)-b-D-Fucp-(1-3)-Subst11Me Subst = olean-12-en-3β,11α,16β,23,28-pentol = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H]){11}[C@H](O)C=C4[C@]5([H])CC(C)(C)CC[C@@]({28}CO)5{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  Reference(s) to other database(s): CCSD:15457, CBank-STR:11914
  
   
  
  Bupleurum marginatum var. stenophyllum
  CSDB ID 119373 (all data & tools)
• Compound ID: 24418
  

  b-D-Glcp3Ac-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin G = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: 3″-O-acetylsaikosaponin d
  Compound class: saponin glycoside
  
   
  
  Bupleurum marginatum var. stenophyllum, Bupleurum rockii
  CSDB ID 219373 (all data & tools)
• Compound ID: 24419
  

  b-D-Glcp6Ac-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin F = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  
   
  
  Bupleurum marginatum var. stenophyllum, Bupleurum marginatum, Bupleurum rockii
  CSDB ID 269373 (all data & tools)
• Compound ID: 24420
  

  b-D-Glcp6Ac-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin G = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: 6″-O-acetylsaikosaponin d
  Compound class: saponin glycoside
  
   
  
  Bupleurum marginatum var. stenophyllum, Bupleurum rockii
  CSDB ID 269374 (all data & tools)
• Compound ID: 24421
  

  b-D-Glcp3Ac-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin F = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: 3″-O-acetylsaikosaponin a
  Compound class: saponin glycoside
  
   
  
  Bupleurum marginatum var. stenophyllum, Bupleurum rockii
  CSDB ID 269375 (all data & tools)
• Compound ID: 24423
  

  b-D-Glcp3Ac-(1-3)-b-D-Fucp-(1-3)-Subst11Me Subst = olean-12-en-3β,11α,16α,23,28-pentol = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H]){11}[C@H](O)C=C4[C@]5([H])CC(C)(C)CC[C@@]({28}CO)5{16}[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  
   
  
  Bupleurum marginatum var. stenophyllum
  CSDB ID 269377 (all data & tools)
• Compound ID: 24430
  

  b-D-Glcp-(1-6)-+ | a-L-Rhap-(1-4)-b-D-Glcp-(1-3)-Subst11Me Subst = olean-12-en-3β,11α,16β,28-tetrol = SMILES C[C@@]1(C){3}[C@@H](O)CC[C@]2(C)[C@@]3([H]){11}[C@H](O)C=C4[C@]5([H])CC(C)(C)CC[C@@]({28}CO)5{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  Reference(s) to other database(s): CCSD:15458, CBank-STR:9935
  
   
  
  Bupleurum marginatum var. stenophyllum, Bupleurum marginatum, Bupleurum rockii
  CSDB ID 119372 (all data & tools)
• Compound ID: 24431
  

  b-D-Glcp-(1-6)-+ | a-L-Rhap-(1-4)-b-D-Glcp-(1-3)-Subst11Me Subst = olean-12-en-3β,11α,16β,23,28-pentol = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H]){11}[C@H](O)C=C4[C@]5([H])CC(C)(C)CC[C@@]({28}CO)5{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  Reference(s) to other database(s): CCSD:15459, CBank-STR:9936
  
   
  
  Bupleurum marginatum var. stenophyllum
  CSDB ID 119374 (all data & tools)
• Compound ID: 24432
  

  b-D-Xylp-(1-2)-b-D-Glcp-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin F = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: chikusaikoside I
  Compound class: saponin glycoside
  Reference(s) to other database(s): CCSD:15460, CBank-STR:9461
  
   
  
  Bupleurum marginatum var. stenophyllum
  CSDB ID 119368 (all data & tools)
• Compound ID: 24433
  

  b-D-Glcp-(1-6)-+ | a-L-Rhap-(1-4)-b-D-Glcp-(1-3)-Subst Subst = saikogenin F = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: chikusaikoside II
  Compound class: saponin glycoside
  Reference(s) to other database(s): CCSD:23058, CBank-STR:7059
  
   
  
  Bupleurum marginatum var. stenophyllum, Bupleurum marginatum
  CSDB ID 119369 (all data & tools)
• Compound ID: 24434
  

  b-D-Glcp-(1-3)-b-D-Fucp-(1-3)-Subst11Me Subst = olean-12-en-3β,11α,16β,23,28-pentol = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H]){11}[C@H](O)C=C4[C@]5([H])CC(C)(C)CC[C@@]({28}CO)5{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  Reference(s) to other database(s): CCSD:937, CBank-STR:8594
  
   
  
  Bupleurum marginatum, Bupleurum marginatum var. stenophyllum
  CSDB ID 119370 (all data & tools)
• Compound ID: 24435
  

  b-D-Glcp-(1-3)-b-D-Fucp-(1-3)-Subst11Me Subst = olean-12-en-3β,11α,16α,23,28-pentol = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H]){11}[C@H](O)C=C4[C@]5([H])CC(C)(C)CC[C@@]({28}CO)5{16}[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  Reference(s) to other database(s): CCSD:948, CBank-STR:8593
  
   
  
  Bupleurum marginatum var. stenophyllum
  CSDB ID 119371 (all data & tools)
• Compound ID: 23794
  

  b-D-Glcp-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin D = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=CC4=C5CC(C)(C)CC[C@@]({28}CO)5{16}[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: saikosaponin a, saikosaponin b2
  Compound class: saponin glycoside, glycoside, steroid glycoside
  Reference(s) to other database(s): CCSD:26960, CBank-STR:5890
  
   
  
  Bupleurum rockii
  CSDB ID 269381 (all data & tools)
• Compound ID: 24422
  

  b-D-Glcp2Ac-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin F = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: 2″-O-acetylsaikosaponin a
  Compound class: saponin glycoside
  
   
  
  Bupleurum rockii
  CSDB ID 269376 (all data & tools)
• Compound ID: 24424
  

  b-D-Glcp6Ac-(1-3)-b-D-Fucp-(1-3)-Subst11Me Subst = olean-12-en-3β,11α,16β,23,28-pentol = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H]){11}[C@H](O)C=C4[C@]5([H])CC(C)(C)CC[C@@]({28}CO)5{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  
   
  
  Bupleurum marginatum, Bupleurum rockii
  CSDB ID 269378 (all data & tools)
• Compound ID: 24425
  

  b-D-Glcp2Ac-(1-3)-b-D-Fucp-(1-3)-Subst11Me Subst = olean-12-en-3β,11α,16β,23,28-pentol = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H]){11}[C@H](O)C=C4[C@]5([H])CC(C)(C)CC[C@@]({28}CO)5{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  
   
  
  Bupleurum rockii
  CSDB ID 269379 (all data & tools)
• Compound ID: 24426
  

  b-D-Glcp3Ac-(1-3)-b-D-Fucp-(1-3)-Subst11Me Subst = olean-12-en-3β,11α,16β,23,28-pentol = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H]){11}[C@H](O)C=C4[C@]5([H])CC(C)(C)CC[C@@]({28}CO)5{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  
   
  
  Bupleurum rockii
  CSDB ID 269380 (all data & tools)
• Compound ID: 24427
  

  b-D-Glcp2Ac-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin D = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=CC4=C5CC(C)(C)CC[C@@]({28}CO)5{16}[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  
   
  
  Bupleurum rockii
  CSDB ID 269382 (all data & tools)
• Compound ID: 24428
  

  b-D-Glcp3Ac-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin D = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=CC4=C5CC(C)(C)CC[C@@]({28}CO)5{16}[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Compound class: saponin glycoside
  
   
  
  Bupleurum rockii
  CSDB ID 269383 (all data & tools)
• Compound ID: 24429
  

  b-D-Glcp6Ac-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin D = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=CC4=C5CC(C)(C)CC[C@@]({28}CO)5{16}[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: 6″-O-acetylsaikosaponin b2
  Compound class: saponin glycoside
  
   
  
  Bupleurum rockii
  CSDB ID 269384 (all data & tools)
• Compound ID: 23796
  

  b-D-Glcp-(1-3)-b-D-Fucp-(1-3)-Subst Subst = saikogenin E = SMILES CC1(C){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: saikosaponin c, saikosaponin e, saikosaponin 3, saikosaponin-e
  Compound class: saponin glycoside, glycoside, triterpenoid glycoside
  Reference(s) to other database(s): CCSD:954, CBank-STR:5891
  
   
  
  Bupleurum marginatum
  CSDB ID 119375 (all data & tools)
• Compound ID: 24436
  

  b-D-Fucp-(1-3)-Subst Subst = saikogenin F = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]

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  Structure type: oligomer
  Trivial name: 3-O-fucopyranosyl-saikogenin F
  Compound class: saponin glycoside
  Reference(s) to other database(s): CCSD:958, CBank-STR:2136
  
   
  
  Bupleurum marginatum
  CSDB ID 119376 (all data & tools)