T cells may recognize glycolipids and lipids of bacterial and self origin associated with the CD1 antigen-presenting molecules. Understanding the mechanisms governing CD1-self glycolipid interaction will provide information on the molecular rules of glycolipid presentation and suggest new approaches to immunotherapy
genetics, molecular, antigens, immunology, review, lipids, glycosphingolipids, glycolipids, models, CD1, glycosphingolipid, physiology, Animals, Humans, Autoantigens, Antigen-Presenting Cells, Autoimmune Diseases, Autoimmunity, Immunotherapy, Lymphocytes, T-Lymphocytes
NCBI PubMed ID: 12644623Journal NLM ID: 8609378Publisher: Bethesda, MD: International Union of Physiological Sciences and the American Physiological Society
Institutions: Experimental Immunology, Department of Research, University Hospital, Basel, CH-4031 Basel, Switzerland