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1. (Article ID: 10527)
Favel A, Steinmetz MD, Regli P, Vidal-Ollivier E, Elias R, Balansard G
In vitro antifungal activity of triterpenoid saponins
Planta Medica 60 (1994)
50-53
The antifungal activity of triterpenoid saponins, with hederagenin or oleanolic acid as aglycone, was investigated in vitro by the agar dilution method. Monodesmosidic hederagenin derivatives were shown to exhibit a broad spectrum of activity against yeast as well as dermatophyte species. α-Hederin was the most active compound, and Candida glabrata was the most susceptible strain. The structure-activity relationships are discussed.
antifungal activity, Candida glabrata, hederagenin, triterpenoid saponins, monodesmosides, dermatophytes
NCBI PubMed ID: 8134417Publication DOI: 10.1055/s-2006-959407Journal NLM ID: 0066751Publisher: George Thieme
Institutions: Laboratoire de Pharmacognosie, Faculté de Pharmacie, Marseille, France, Laboratoire de Botanique et Cryptogamie, Faculté de Pharmacie, Marseille, France
The publication contains the following compound(s):
- Compound ID: 25062
|
b-D-Galp-(1-3)-+
|
b-D-Glcp-(1-2)-b-D-GlcpA-(1-3)-Oleanolic
Oleanolic = 3β-hydroxyolean-12-en-28-oic acid |
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Structure type: oligomer
Trivial name: saponoside S2
Compound class: saponin glycoside
Reference(s) to other database(s): CCSD:
34086, CBank-STR:8722
- Compound ID: 25064
|
b-D-Galp-(1-3)-b-D-Glcp-(1-3)-Oleanolic
Oleanolic = 3β-hydroxyolean-12-en-28-oic acid |
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Structure type: oligomer
Trivial name: arvensoside B
Compound class: saponin glycoside
Reference(s) to other database(s): CCSD:
34084, CBank-STR:5371
- Compound ID: 25066
|
b-D-Galp-(1-3)-+
|
b-D-Glcp-(1-2)-b-D-Glcp-(1-3)-Oleanolic
Oleanolic = 3β-hydroxyolean-12-en-28-oic acid |
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Structure type: oligomer
Trivial name: arvensoside D
Compound class: saponin glycoside
Reference(s) to other database(s): CCSD:
34085, CBank-STR:8715
- Compound ID: 23964
Structure type: oligomer
C41H66O12
Trivial name: Kalopanax-saponin A, α-hederin, kalopanaxsaponin A
Compound class: saponin glycoside, glycoside, triterpenoid glycoside
Reference(s) to other database(s): CCSD:
39886, CBank-STR:2464
- Compound ID: 25069
Structure type: oligomer
Trivial name: akeboside Stb leontoside A β-2-fatsin, akeboside Stb, leontoside A, β-2-fatsin, hederin
Compound class: saponin glycoside
Reference(s) to other database(s): CCSD:
34079, CBank-STR:525
- Compound ID: 25910
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b-D-Glcp-(1-3)-Subst
Subst = presenegenin = SMILES C[C@@]12CC[C@@H]3[C@@](C{2}[C@H](O){3}[C@H](O)[C@]3({23}C(O)=O)C)(C)[C@H]1CC=C4[C@@]2({27}CO)CC[C@]5({28}C(O)=O)[C@H]4CC(C)(C)CC5 |
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Structure type: oligomer
Trivial name: tenuifolin
Compound class: saponin glycoside
Reference(s) to other database(s): CCSD:
34087, CBank-STR:967
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