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1. (Article ID: 10714)
Sekine T, Arai Y, Ikegami F, Fujii Y, Shindo S, Yanagisawa T, Ishida Y, Okonogi S, Murakoshi I
Isolation of camelliaside C from 'tea seed cake' and inhibitory effects of its derivatives on arachidonate 5-lipoxygenase
Chemical and Pharmaceutical Bulletin 41 (1993)
1185-1187
A new flavonol glycoside, camelliaside C, was isolated from "tea seed cake" prepared from the defatted seeds of Camellia sinensis O. KUNTZE. The structure was determined as kaempferol 3-O-β-D-galactopyranosyl-(1→2)-β-D-glucopyranoside by spectroscopic methods (FAB-MS, UV, IR, ^1H- and ^<13>C-NMR) and the enzymatic transformation of camelliaside C to astragalin. Camelliaside C showed an inhibitory effect on the arachidonate 5-lipoxygenase of RBL-1 cells (IC_<50> : 1.4×10^<-4> M) as did camelliaside A and B isolated from the same product.
Camellia sinensis, Theaceae, camelliaside C, arachidonate 5-lipoxygenase inhibitor, tea seed cake
Journal NLM ID: 0377775WWW link: http://ci.nii.ac.jp/naid/110003630580Publisher: Pharmaceutical Society Of Japan
Institutions: Faculty of Pharmaceutical Sciences, Chiba University, Japan, Tsumura Research Institute of Pharmacology, Japan, Faculty of Pharmacy, Chiang Mai University, Thailand
Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, acid hydrolysis, HPLC, enzymatic digestion, biological assay
The publication contains the following compound(s):
- Compound ID: 20822
Structure type: oligomer
C27H30O16
Trivial name: rutin, rutoside, rutin, quercetin rutinoside, rutoside, quercetin 3-O-rutinose, quercetin-3-O-rutinoside, quercetin 3-O-rutinoside
Compound class: saponin glycoside, glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside
Reference(s) to other database(s): CCSD:
50720, CBank-STR:3399
- Compound ID: 25908
Structure type: oligomer
C27H30O15
Trivial name: nicotiflorin
Compound class: glycoside, flavonoid glycoside, flavonol glycoside
Reference(s) to other database(s): CCSD:
41325, CBank-STR:3415
- Compound ID: 26207
Structure type: oligomer
Trivial name: leucoside
Compound class: glycoside, flavonol glycoside, flavone glycoside
Reference(s) to other database(s): CCSD:
40059, CBank-STR:4019
- Compound ID: 26337
Structure type: monomer
Trivial name: astragalin, kaempferol 3-O-glucoside
Compound class: glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside
Reference(s) to other database(s): CCSD:
49928, CBank-STR:4070
- Compound ID: 26614
Structure type: oligomer
; 611 [M+H]+
C27H30O15
Trivial name: camelliaside C
Compound class: flavonol glycoside
Reference(s) to other database(s): CCSD:
40055, CBank-STR:5374
- Compound ID: 26615
Structure type: oligomer
Trivial name: camelliaside A
Compound class: flavonol glycoside
Reference(s) to other database(s): CCSD:
40057, CBank-STR:8589
- Compound ID: 26616
Structure type: oligomer
Trivial name: camelliaside B
Compound class: flavonol glycoside
Reference(s) to other database(s): CCSD:
40058, CBank-STR:4913
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