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1. (Article ID: 10832)
 
Tomoda M, Gonda R, Shimizu N, Ohara N
Characterization of an acidic polysaccharide having immunological activities from the tuber of Alisma orientale
Biological and Pharmaceutical Bulletin 17 (1994) 572-576
 

An acidic polysaccharide, called alisman PII, was isolated from the tuber of Alisma orientale Juzepcz. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 5.25 x 10(4). It is composed of L-arabinose:D-galactose:D-glucuronic acid in the molar ratio of 4:9:2, in addition to some of O-acetyl groups. Reduction of carboxyl groups, methylation analysis, nuclear magnetic resonance and controlled Smith degradation indicated that the core structural features include a backbone chain composed of β-1,3-linked D-galactose units. Some of the galactose units in the backbone carry β-D-galactosyl side chains at position 6. Both α-1,5-linked L-arabinosyl side chains and terminal β-D-glucuronic acid residues are linked to the core galactan units. Alisman PII showed significant potentiation of the reticuloendothelial system using a carbon clearance test and also potent anti-complementary activity.

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2. (Article ID: 11304)
 
Ovodov IS
Polysaccharides of flower plants: structure and physiological activity
Bioorganicheskaya Khimia = Bioorganic Chemistry [Russian] 24(7) (1998) 483-501
 

The results of studies on the chemical structure and physiological activity of phanerogam polysaccharides, accumulated within the last two decades, are reviewed. Three types of polysaccharides are considered: rhamnogalacturonans (pectins and related gums and mucilages, type A), acidic arabinogalactans (mainly plant mucilages, gums, and some hemicelluloses, type B), and neutral glucans and heteroglycans (reserve polysaccharides, type C). Various physiological activities of these plant polysaccharides are discussed, with particular emphasis being placed on their immunomodulatory action. The data available on the relationship between chemical structure and physiological activity of plant polysaccharides are considered. Information on the medicinal use of some plants containing physiologically active polysaccharides is presented.

полисахариды растений, пектины, арабино-3, 6-галактаны, а-1, 4-глюканы, физиологическая активность, иммуномодуляторы

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