Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
The structure was elucidated in this paperNCBI PubMed ID: 27329160Publication DOI: 10.1007/s00792-016-0858-2Journal NLM ID: 9706854Publisher: Springer
Correspondence: corsaro
unina.it
Institutions: National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, County Dublin, Ireland, Division of Bioanalytical Chemistry, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Parkallee 10, 23845, Borstel, Germany, Istituto di Chimica Biomolecolare ICB-CNR, Via Campi Flegrei 34, 80078, Pozzuoli, Italy, Department of Experimental Medicine, Second University of Naples, via de Crecchio 7, 80138, Naples, Italy, Dipartimento di Scienze Chimiche, Universita di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126, Naples, Italy
Halomonas pantelleriensis DSM9661T is a Gram-negative haloalkaliphilic bacterium isolated from the sand of the volcanic Venus mirror lake, closed to seashore in the Pantelleria Island in the south of Italy. It is able to optimally grow in media containing 3-15 % (w/v) total salt and at pH between 9 and 10. To survive in these harsh conditions, the bacterium has developed several strategies that probably concern the bacteria outer membrane, a barrier regulating the exchange with the environment. In such a context, the lipopolysaccharides (LPSs), which are among the major constituent of the Gram-negative outer membrane, are thought to contribute to the restrictive membrane permeability properties. The structure of the lipid A family derived from the LPS of Halomonas pantelleriensis DSM 9661T is reported herein. The lipid A was obtained from the purified LPS by mild acid hydrolysis. The lipid A, which contains different numbers of fatty acids residues, and its partially deacylated derivatives were completely characterized by means of ESI FT-ICR mass spectrometry and chemical analysis. Preliminary immunological assays were performed, and a comparison with the lipid A structure of the phylogenetic proximal Halomonas magadiensis is also reported.
lipopolysaccharides, lipid A, mass spectrometry, Extremophile, Halomonas, phylogenetic, haloalkaliphilic
Structure type: oligomer
Location inside paper: p.691, fig.3
Compound class: lipid A
Contained glycoepitopes: IEDB_137340,IEDB_141807,IEDB_151531,IEDB_534864
Methods: GC-MS, chemical analysis, ESI-MS, mild acid hydrolysis, alkaline hydrolysis, immunological assays, SI-FTICR-MS
NCBI Taxonomy refs (TaxIDs): 48727
Show glycosyltransferases
There is only one chemically distinct structure:
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