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1. (Article ID: 11372)
 
Bedir E, Calis I, Zerbe O, Sticher O
Cyclocephaloside I: A novel cycloartane-type glycoside from Astragalus microcephalus
Journal of Natural Products 61(4) (1998) 503-505
 

A novel cycloartane-type glycoside, cyclocephaloside I (1) was isolated from the roots of Astragalus microcephalus in addition to known glycosides cyclocanthoside E (2) and astragaloside IV (3). The structure of 1 was determined by spectral (IR, H-1 and C-13 NMR, and FABMS) and chemical (acetylation) methods and established as 20,25-epoxy-3 beta-(beta-D-xylopyranosyl)oxy-6 alpha-(beta-D-glucopyranosyl)oxy-cycloartane-16 beta,24 alpha-diol.

NMR, cycloartane, Astraglus

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2. (Article ID: 11798)
 
Lee SJ, Yun YS, Lee IK, Ryoo IJ, Yun BS, Yoo ID
An antioxidant lignan and other constituents from the root bark of Hibiscus syriacus
Planta Medica 65(7) (1999) 658-660
 

A new lignan named as hibiscuside, (+)-pinoresinol 4-O-[β-glucopyranosyl(1→2)-α-rhamnoside] (1), and a known lignan, syringaresinol (2) were isolated from the root bark of Hibiscus syriacus together with two feruloyltyramines (3,4) and three known isoflavonoids (5,6,7). The structures of these compounds have been established on the basis of their NMR, mass, UV spectra. Among these phenolic compounds, 6″-O-acetyldaidzin (5), 6″-O-acetylgenistin (6), and 3′-hydroxydaidzein (7) with IC50 values of 8.2, 10.6, and 4.1 µM, respectively, significantly inhibited lipid peroxidation in rat liver microsomes. Hibiscuside (1), E- and Z-N-feruloyl tyramines (3,4) exhibited moderate antioxidant activity.

flavonoid glycoside, lignan glycoside, Hibiscus syriacus, hibiscuside

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