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1. (Article ID: 11458)
 
Haraguchi H, Kanada M, Fukuda A, Naruse K, Okamura N, Yagi A
An inhibitor of aldose reductase and sorbitol accumulation from Anthocepharus chinensis
Planta Medica 64(1) (1998) 68-69
 

A flavonoid glycoside was isolated from Anthocepharus chinensis. Its structure was elucidated by spectral data and determined to be myricetin 3-O-(4"-acetyl)-alpha-fucoside. This flavonoid glycoside and its aglycone showed potent inhibition against rat and porcine lens aldose reductase. The flavonoid aglycone also inhibited sorbitol accumulation in human red blood cells.

Enzymes, derivatives, flavonoids

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