Found 1 publication.
Displayed publication 1
Expand all publications
Collapse all publications
Show all as text (SweetDB notation)
Show all graphically (SNFG notation)
1. (Article ID: 11465)
Kim HJ, Woo ER, Shin CG, Park H
A new flavonol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase
Journal of Natural Products 61(1) (1998)
145-148
Bioassay-directed chromatographic fractionation of an ethyl acetate extract of the leaves of Acer okamotoanum using HIV-1 integrase afforded a new acylated flavonol glycoside, quercetin 3-0-(2 ",6 "-0-digalloyl)-beta-D-galactopyra (1), together with six known flavonol glycosides and three known phenolic compounds. The structure of the new compound was determined by spectroscopic methods. The most active compounds were quercetin 3-O-(2 "-galloyl)-alpha-L-arabinopyranoside (6) and 1, which exhibited IC50 values of 18.1 +/- 1.3 and 24.2 +/- 6.6 mu g/mL, respectively, against HIV-1 integrase.
iridoid glucosides, secoiridoid glucosides, loganic acid, loganin, Loasa acerifolia, Loasaceae, acerifolioside, tricoloroside methyl ester
NCBI PubMed ID: 9461665Publication DOI: 10.1021/np970171qJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: Woo ER
kistmail.kist.re.kr>
Institutions: Division of Applied Science, Korea Institute of Science & Technology, Seoul, South Korea, Department of Biotechnology, Chung-Ang University, An-Sung, Korea
Methods: 13C NMR, 1H NMR, IR, inhibition studies, TLC, ESI-MS, acid hydrolysis, MS, UV, extraction, optical rotation measurement, CC, melting point determination, HMBC, HR-FAB-MS
The publication contains the following compound(s):
- Compound ID: 29259
Structure type: monomer
; 769.1251 [M+H]+
C35H28O20
Compound class: glycoside
- Compound ID: 29260
|
/Variants 0/-Quercetin
/Variants 0/ is:
b-D-Galp-(1-3)-
OR (exclusively)
a-L-Rhap-(1-3)- |
Show graphically |
Structure type: monomer
Compound class: glycoside
- Compound ID: 29261
|
/Variants 0/-Kaempferol
/Variants 0/ is:
a-L-Rhap-(1-3)-
OR (exclusively)
a-L-Arap-(1-3)- |
Show graphically |
Structure type: monomer
Compound class: glycoside
- Compound ID: 29262
Structure type: monomer
Compound class: glycoside
- Compound ID: 29263
Structure type: monomer
Compound class: glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside
- Compound ID: 29264
|
Gallic-(7-2)-+
|
?%Gallic-(7-4)-+ |
| |
?%Gallic-(7-3)-b-D-Glcp
| |
Gallic-(7-1)-+ |
|
Gallic-(7-6)-+ |
Show graphically |
Structure type: monomer
Compound class: glycoside
Expand this publication
Collapse this publication
Total list of publication IDs on all result pages of the current query:
Total list of corresponding CSDB IDs (permanent record IDs):
Execution: <1 sec