A cardenolide glycoside was isolated from the aerial parts of Gomphocarpus sinaicus Boiss. along with the previously known cardenolide glycoside 15β-hydroxycalotropin. The structure of the new glycoside was elucidated on the basis of spectroscopic data and comparison of NMR data with those of the congeners. It was identified as 15β-hydroxy-7,8- dehydrocalotropin.

Asclepiadaceae, aerial parts, Δ7-cardenolides, Gomphocarpus sinaicus

• Compound ID: 29787
  

  b-D-Sug-(1-3:2-2)-Subst Sug = 4,6-dideoxyglucose = SMILES C[C@@H]1C{3}[C@H](O){2}[C@@H](O){1}[C@H](O)O1; Subst = 5β-hydroxy-7,8-dehydrocalotropin aglycon = SMILES C[C@]34CC[C@H]2/C(=C\C[C@H]1C{3}[C@@H](O){2}[C@H](O)C[C@@]12C=O){14}[C@@]3(O){15}[C@H](O)C[C@@H]4/C5=C/C(=O)OC5

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  Structure type: monomer ; 545 [M-H]-
  C29H38O10
  Trivial name: 15β-hydroxy-7,8-dehydrocalotropin
  Compound class: glycoside
  
   
  
  Gomphocarpus sinaicus
  CSDB ID 63524 (all data & tools)
• Compound ID: 29788
  

  b-D-Sug-(1-3:2-2)-Subst Sug = 4,6-dideoxyglucose = SMILES C[C@@H]1C{3}[C@H](O){2}[C@@H](O){1}[C@H](O)O1; Subst = 15β-hydroxy-calotropin aglycon = SMILES C[C@]34CC[C@H]2C(CC[C@H]1C{3}[C@@H](O){2}[C@H](O)C[C@@]12C=O){14}[C@@]3(O){15}[C@H](O)C[C@@H]4/C5=C/C(=O)OC5

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  Structure type: monomer ; 547 [M-H]-
  Trivial name: 15β-hydroxy-calotropin
  Compound class: glycoside
  
   
  
  Gomphocarpus sinaicus
  CSDB ID 63719 (all data & tools)