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1. (Article ID: 11816)
 
Passreiter CM, De Carlo M, Steigel A
Sesquiterpene lactone glycosides from Arnica longifolia
Planta Medica 65(2) (1999) 153-156
 

Flowers of Arnica longifolia were investigated for the occurrence of sesquiterpene lactone glycosides. A mixture containing the two isomeric 11α,13-dihydro- and 11β,13-dihydro-4H-tomentosin glucosides, previously isolated from A. amplexicaulis and A. mollis, together with the two isomeric 11α,13-dihydro- and 11β,13-dihydro-4H-carabrone glucosides were found in A. longifolia. All carbon and proton shifts of the glycosides could be assigned by their 2D-COSY and 2D-HETCOR spectra and spectroscopy of their respective aglycones, obtained via enzymatic hydrolysis.

Asteraceae, sesquiterpene lactones, sesquiterpene lactone glycosides, Arnica longifolia, xanthanolides, xanthanolide glucosides, carabrone glucosides

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2. (Article ID: 11819)
 
Passreiter CM, Merfort I, Bestendonk C, Willuhn G, Steigel A
11α,13- and 11β,13-dihydro-4H-xanthalongin 4-O-β-glucopyranosides: new sesquiterpene lactone glycosides from flowers of Arnica amplexicaulis and A. mollis
Planta Medica 62(1) (1996) 39-41
 

The flowers of A. amplexicaulis afforded, in addition to xanthalongin (1), 11β,13-dihydroxanthalongin (2), its 11-epimer (3), and 11α,13-dihydro-4H-xanthalongin (4), the new xanthanolide glycosides 11α,13-dihydro-4H-xanthalongin 4-O-β-D-glucopyranoside (5) and its 11-epimer (6). The glycosides were also isolated from the flowers of A. mollis. The structures were elucidated by NMR spectroscopy 1H-NMR, COSY, 13C-NMR, HETCOR, DEPT), MS (EI, FAB, FD), and enzymatic hydrolysis of the glycosides. The chemo-taxonomic importance is discussed.

chemotaxonomy, Asteraceae, sesquiterpene lactones, Arnica amplexicaulis, A. mollis, xanthanolides and xanthanolide glucosides

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