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1. (Article ID: 11977)
 
Adesina SK, Idowu O, Ogundaini AO, Oladimeji H, Olugbade TA, Onawunmi GO, Païs M
Antimicrobial constituents of the leaves of Acalypha wilkesiana and Acalypha hispida
Phytotherapy Research 14(5) (2000) 371-374
 

An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity. Quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside were also isolated from the inactive fraction of A. hispida. The structures were established by permethylation, 2D - NMR ((1)H and (13)C) and MS data.

antimicrobial, Acalypha wilkesiana, Acalypha hispida, corilagin, geraniin

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