Taxonomic group: plant / Streptophyta
(Phylum: Streptophyta)
Organ / tissue: seed
Journal NLM ID: 0377775WWW link: http://ci.nii.ac.jp/naid/110003630580Publisher: Pharmaceutical Society Of Japan
Institutions: Faculty of Pharmaceutical Sciences, Chiba University, Japan, Tsumura Research Institute of Pharmacology, Japan, Faculty of Pharmacy, Chiang Mai University, Thailand
A new flavonol glycoside, camelliaside C, was isolated from "tea seed cake" prepared from the defatted seeds of Camellia sinensis O. KUNTZE. The structure was determined as kaempferol 3-O-β-D-galactopyranosyl-(1→2)-β-D-glucopyranoside by spectroscopic methods (FAB-MS, UV, IR, ^1H- and ^<13>C-NMR) and the enzymatic transformation of camelliaside C to astragalin. Camelliaside C showed an inhibitory effect on the arachidonate 5-lipoxygenase of RBL-1 cells (IC_<50> : 1.4×10^<-4> M) as did camelliaside A and B isolated from the same product.
Camellia sinensis, Theaceae, camelliaside C, arachidonate 5-lipoxygenase inhibitor, tea seed cake
Structure type: monomer
Location inside paper: 2
Trivial name: astragalin, kaempferol 3-O-glucoside
Compound class: glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, acid hydrolysis, HPLC, enzymatic digestion, biological assay
Biological activity: arachidonate 5-lipoxygenase inhibitor
Related record ID(s): 62230
NCBI Taxonomy refs (TaxIDs): 4442Reference(s) to other database(s): CCSD:
49928, CBank-STR:4070
Show glycosyltransferases
There is only one chemically distinct structure:
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