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1. (Article ID: 12647)
Samuelsen AB
The traditional uses, chemical constituents and biological activities of Plantago major L. A review
Journal of Ethnopharmacology 71(1-2) (2000)
1-21
Plantago major L. leaves have been used as a wound healing remedy for centuries in almost all parts of the world and in the treatment of a number of diseases apart from wound healing. These include diseases related to the skin, respiratory organs, digestive organs, reproduction, the circulation, against cancer, for pain relief and against infections. P. major contains biologically active compounds such as polysaccharides, lipids, caffeic acid derivatives, flavonoids, iridoid glycosides and terpenoids. Alkaloids and some organic acids have also been detected. A range of biological activities has been found from plant extracts including wound healing activity, anti-inflammatory, analgesic, antioxidant, weak antibiotic, immuno modulating and antiulcerogenic activity. Some of these effects may attribute to the use of this plant in folk medicine.
traditional uses; chemical constituents; biological activities; Plantago major L
NCBI PubMed ID: 10904143Publication DOI: 10.1016/s0378-8741(00)00212-9Journal NLM ID: 7903310Publisher: Limerick: Elsevier Sequoia
Correspondence: a.b.samuelsen
farmasi.uio.no
Institutions: Department of Pharmacognosy, School of Pharmacy, University of Oslo, Oslo, Norway
The publication contains the following compound(s):
- Compound ID: 21982
Structure type: monomer
Trivial name: cosmosiin, apigenin 7-O-glucoside, rhoifolin, apigenin 7-glucoside, apigetrin
Compound class: glycoside, flavonoid glycoside, flavonol glycoside
Reference(s) to other database(s): CCSD:
50502, CBank-STR:1305
- Compound ID: 22429
Structure type: oligomer
Trivial name: acteoside, verbascoside, acteoside, verbascoside, trans-verbascoside, verbascoside, acteoside
Compound class: saponin glycoside, glycoside, phenolic glycoside, phenylethanoid glycoside, phenylpropanoid glycoside, iridoid glycoside, lignan glycoside
- Compound ID: 26872
Structure type: monomer
Trivial name: glucoluteolin, luteolin 7-glucoside
Compound class: saponin glycoside, glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside, flavone glucoside
Reference(s) to other database(s): CCSD:
50066, CBank-STR:939
- Compound ID: 28027
Structure type: oligomer
Trivial name: plantamajoside, plantaginin
Compound class: saponin glycoside, glycoside, phenolic glycoside, lignan glycoside, phenylpropanoid glucoside
- Compound ID: 28585
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b-D-Glcp-(1-1)-Subst
Subst = aucubin aglycon = SMILES O{10}CC1=C{6}[C@@H](O)[C@H]2[C@@H]1{1}[C@H](O)OC=C2 |
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Structure type: monomer
Trivial name: aucubin
Compound class: glycoside, iridoid glycoside
- Compound ID: 32607
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b-D-Glcp-(1-7)-Subst
Subst = hispidulin = SMILES COc1{7}c(O)cc2oc(-c3cc{54}c(O)cc3)cc(=O)c2{5}c1O |
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Structure type: monomer
Compound class: glycoside, flavonoid glycoside
- Compound ID: 32762
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b-D-GlcpA-(1-7)-Subst
Subst = hispidulin = SMILES COc1{7}c(O)cc2oc(-c3cc{54}c(O)cc3)cc(=O)c2{5}c1O |
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Structure type: monomer
Compound class: glycoside, flavonoid glycoside
- Compound ID: 32763
Structure type: oligomer
Compound class: glycoside, flavonoid glycoside
- Compound ID: 32764
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b-D-Galp-(1-7)-Subst4'Me
Subst = 6-hydroxyluteolin = SMILES O=C(C1={5}C(O){6}C(O)={7}C(O){8}C=C1O2)C=C2C3=C{53}C(O)={54}C(O)C=C3 |
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Structure type: monomer
Compound class: glycoside, flavonoid glycoside
- Compound ID: 32765
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b-D-Glcp-(1-7)-Subst
Subst = scutellarein = SMILES O=C(C1=C(C={7}C(O){6}C(O)={5}C1O)O2)C=C2C3=CC={54}C(O)C=C3 |
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Structure type: monomer
Trivial name: plantaginin
Compound class: glycoside, flavonoid glycoside
- Compound ID: 26382
Structure type: monomer
Trivial name: catalpol
Compound class: glycoside, iridoid glycoside
Reference(s) to other database(s): CCSD:
39192, CBank-STR:1056
- Compound ID: 29506
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b-D-Glcp-(1-1)-Subst
Subst = geniposidic acid aglycon = SMILES O={11}C(C1=CO{1}[C@@H](O)[C@@]2([H])[C@]1([H])CC=C2{10}CO)O |
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Structure type: monomer
Trivial name: geniposidic acid
Compound class: glycoside, iridoid glycoside
- Compound ID: 32766
Structure type: monomer
Trivial name: majoroside
Compound class: glycoside, iridoid glycoside
- Compound ID: 32767
Structure type: monomer
Trivial name: 10-hydroxymajoroside
Compound class: glycoside, iridoid glycoside
- Compound ID: 32768
Structure type: monomer
Trivial name: 10-acetoxymajoroside
Compound class: glycoside, iridoid glycoside
- Compound ID: 32769
Structure type: monomer
Trivial name: melittoside
Compound class: glycoside, iridoid glycoside
- Compound ID: 31425
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b-D-Glcp-(1-1)-Subst
Subst = asperuloside aglycon = SMILES O{10}CC1=C[C@H]2[C@H]3[C@@H]1{1}[C@H](O)OC=C3C(O2)=O |
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Structure type: monomer
C18H22O11
Trivial name: asperuloside, deacetylasperuloside
Compound class: glycoside, iridoid glycoside
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2. (Article ID: 12648)
Sánchez-Contreras S, Diaz-Lanza AM, Bernabé M
Four new triterpenoid saponins from the roots of Bupleurum rigidum
Journal of Natural Products 63(11) (2000)
1479-1482
Five triterpenoid saponins [buddlejasaponin IV, sandrosaponins VII (1), VIII (2), IX (3), and X (4)] were isolated from an n-BuOH extract of the roots of Bupleurum rigidum. Sandrosaponins VII-X (1-4) are new compounds, and their structures were established by 1D and 2D NMR techniques, FABMS, and chemical methods.
saponins, Bupleurum rigidum, buddlejasaponin IV, sandrosaponins VII-X
NCBI PubMed ID: 11087587Publication DOI: 10.1021/np000004hJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: Díaz-Lanza AM
farma.alcala.es>
Institutions: Departamento de Química Orgánica Biológica, Instituto de Química Orgánica General, CSIC, Madrid, Spain, Laboratorio de Farmacognosia, Departamento de Farmacología, Facultad de Farmacia, Universidad de Alcalá de Henares, Alcalá de Henares, Spain
Methods: 13C NMR, 1H NMR, NMR-2D, FAB-MS, TLC, ESI-MS, HPLC, extraction, CC
The publication contains the following compound(s):
- Compound ID: 25202
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b-D-Glcp-(1-3)-+
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b-D-Glcp-(1-2)-b-D-Fucp-(1-3)-Subst
Subst = saikogenin F = SMILES C[C@@]1({23}CO){3}[C@@H](O)CC[C@]2(C)[C@@]3([H])C=C[C@]45[C@]6([H])CC(C)(C)CC[C@@](CO5)6{16}[C@@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H] |
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Structure type: oligomer
Trivial name: buddlejasaponin IV, sandrosaponin VII
Compound class: saponin glycoside, glycoside, triterpenoid glycoside
Reference(s) to other database(s): CCSD:
39348, CBank-STR:9530
- Compound ID: 32770
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b-D-Glcp-(1-3)-+
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b-D-Glcp-(1-2)-b-D-Fucp-(1-3)-Subst
Subst = sandrosaponin II,VII aglycon = SMILES O{3}[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2C=C[C@@]45[C@@]3(C)C{16}[C@H](O)[C@]6(CO5)[C@H]4C[C@](C)({29}CO)CC6)[C@@]1({23}CO)C |
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Structure type: oligomer
Trivial name: sandrosaponin VIII
Compound class: glycoside, triterpenoid glycoside
- Compound ID: 32771
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b-D-Glcp-(1-2)-+
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S-4)-b-D-Glcp-(1-3)-b-D-Fucp-(1-3)-Subst
Subst = sandrosaponin VIII aglycon = SMILES O{3}[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2C=CC4=C5C[C@@]({29}CO)({30}C(O)=O)CC[C@]5(C){16}[C@H](O)C[C@]43C)[C@@]1({23}CO)C |
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Structure type: oligomer
Trivial name: sandrosaponin IX
Compound class: glycoside, triterpenoid glycoside
- Compound ID: 32772
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b-D-Glcp-(1-28)-+
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b-D-Glcp-(1-2)-b-D-Galp-(1-2)-b-D-GlcpA-(1-3)-Oleanolic |
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Structure type: oligomer
Trivial name: sandrosaponin X
Compound class: glycoside, triterpenoid glycoside
- Compound ID: 32773
Structure type: oligomer
Trivial name: buddlejasaponin IV
Compound class: glycoside, triterpenoid glycoside
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