Four new compounds, the limonoid 24-epi-melianodiol (8), the tirucallane aglaiodiol (9), and the two cyclopentatetrahydrobenzopyran derivatives pyramidaglain A (11) and B (12) were isolated from the leaves of Aglaia andamanica Hiern (Meliaceae), together with the eleven known constituents β-sitosterol, β-sitosterol glucoside, cycloart-23E-ene-3β,25-diol (1), three flavonoids 5-hydroxy-3,4′,7-trimethoxyflavone (2), retusin (3) and pachypodol (4), the tirucallane 24-epi-piscidinol A (5), the lignan yangambin (6), the limonoid melianodiol (7), the bisamide pyramidatine (10) and the amino acid N-methyl-trans-4-hydroxy-L-proline (13). All structures were established by means of detailed spectroscopic analysis.

Meliaceae, Aglaia andamanica, 24-epi-melianodiol, aglaiodiol, pyramidaglain A and B

NCBI PubMed ID: 11199132
Publication DOI: 10.1055/s-2000-9901
Journal NLM ID: 0066751
Publisher: George Thieme
Correspondence: awfrahmruf.uni-freiburg.de
Institutions: Department of Pharmaceutical Chemistry, Institut of Pharmaceutical Sciences, University of Freiburg, Freiburg, Germany
Methods: 13C NMR, 1H NMR, NMR-2D, FAB-MS, TLC, ESI-MS, HPLC, extraction, CC
 

• Compound ID: 20490
  

  b-D-Glcp-(1-3)-Subst Subst = β-sitosterol = SMILES O{3}[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@@]2([H])CC[C@@]4(C)[C@]3([H])CC[C@]4([C@@H](C)CC[C@@H](CC)C(C)C)[H]

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  Structure type: monomer
  Trivial name: daucosterol, β-daucosterol, β-sitosterol, β-sitosterol-β-D-glucoside, androsine, saxifragifolin B, β-sitosterol 3-O-β-D-glucopyranoside
  Compound class: saponin glycoside, glycoside, steroid glycoside, triterpenoid glycoside
  Reference(s) to other database(s): GenDB:MK026953.1
  
   
  
  Aglaia andamanica
  CSDB ID 67799 (all data & tools)