Found 1 publication. Displayed publication 1
Expand all publications       Show all as text (SweetDB notation)
1. (Article ID: 1278)
 
Swierzko A, Shashkov AS, Senchenkova SN, Toukach FV, Ziolkowski A, Cedzynski M, Paramonov NA, Kaca W, Knirel YA
Structural and serological studies of the O-specific polysaccharide of the bacterium Proteus mirabilis O10 containing L-altruronic acid, a new component of O-antigens
FEBS Letters 398 (1996) 297-302
 

An acidic O-specific polysaccharide from the lipopolysaccharide of Proteus mirabilis O10 contains 2-acetamido-2-deoxy-D-glucose, 2-acetamido-2-deoxy-D-galactose, D-galacturonic acid, and L-altruronic acid, the last-named sugar having not been found hitherto in O-antigens. Structure of a branched tetrasaccharide repeating unit of the polysaccharide was established by 1H and 13C NMR spectroscopy, including two-dimensional COSY and rotating-frame NOE spectroscopy. The lateral L-altruronic acid residue plays the immunodominant role in manifestation of the O10 specificity of Proteus, whereas a disaccharide fragment of the main chain in common with the O-specific polysaccharide of P. mirabilis O43 provides the one-way serological cross-reactivity between anti-O10 serum and O43-antigen.

Lipopolysaccharide, NMR, LPS, structure, structural, polysaccharide, O-antigen, O antigen, acidic, acid, O antigens, O-antigens, bacteria, O-specific, O-specific polysaccharide, Proteus, Proteus mirabilis, serological, serogroup, bacterial polysaccharide structure, component, D-galacturonic acid, L-altruronic acid, lipopolysaccharide serological specificity

The publication contains the following compound(s):
 

Expand this publication

Resort publications by:

New query Export IDs Home Help

Execution: <1 sec