Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
NCBI PubMed ID: 7844640Journal NLM ID: 0402640Publisher: University of Tokyo Press
Institutions: Department of Food and Nutrition, Faculty of Human Life Science, Osaka City University, Japan
Tritium-labeled antitumor β-D-glucan derivative (T-labeled glucan) was prepared from the branched β-1,3-D-glucan of an edible mushroom, Volvariella volvacea, by its periodate oxidation followed by reduction with NaBT4. Twenty-three hours after T-labeled glucan had been injected into the mouse peritoneal cavity, about 3% of the total radioactivity injected was found in the mouse serum. In spite of the fact that T-labeled glucan had no affinity to the anion-exchange column before injection, about 50% of the labeled β-D-glucan in the serum thus obtained was adsorbed onto the column. The labeled β-D-glucan fraction eluted from the column by salt gradient showed antitumor activity in vivo.
Structure type: homopolymer ; n is large
Trivial name: β-1,3-glucan, pachyman, curdlan, SSG
Compound class: EPS, glucan, cell wall glucan, cell wall glucoprotein
Contained glycoepitopes: IEDB_1397514,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_158555,IEDB_161166,IEDB_558869,IEDB_857743,IEDB_983931,SB_192
Comments, role: branched
Related record ID(s): 103899, 106266, 110076, 110100, 110138, 111873, 111972, 111976, 118123, 125281, 125854, 126051, 130953, 130960, 130963, 139820, 139829, 149482
NCBI Taxonomy refs (TaxIDs): 36659Reference(s) to other database(s): GTC:G51056AN, GlycomeDB:
157, CCSD:
50422, CBank-STR:4225
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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