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Structure type: monomer
Trivial name: myxoxanthophyll
Compound class: glycolipid
Contained glycoepitopes: IEDB_136105,IEDB_225177,IEDB_885823

• Article ID: 5587
  Rezanka T, Dembitsky VM "Metabolites produced by cyanobacteria belonging to several species of the family Nostocaceae" - Folia Microbiologica 51(3) (2006) 159(82)
  

  This paper provides a comprehensive overview of metabolites, including lipids and lipid-like compounds, nitrogen metabolites, oligopeptides and amino acid derivatives, produced by cyanobacteria of the genera Anabaenopsis, Aphanizomenon, Aulosira, Cylindrospermopsis, Cylindrospermum, Nodularia, and Richelia of the family Nostocaceae

  cyanobacteria, lipids, metabolites

  NCBI PubMed ID: 17004647
  Publication DOI: 10.1007/bf02932119
  Journal NLM ID: 0376757
  Publisher: New York: Springer
  Correspondence: rezanka@biomed.cas.cz
  Institutions: Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech, Department of Organic Chemistry, Hebrew University of Jerusalem, Jerusalem, Israel
  Methods: glycolipid
  
   
  
  Aphanizomenon flos-aquae
  CSDB ID 47430 (all data & tools)

Show legend Show as text

Structure type: monomer
Trivial name: myxoxanthophyll
Compound class: glycoside
Contained glycoepitopes: IEDB_130699,IEDB_136045,IEDB_142489,IEDB_144562,IEDB_152214,IEDB_174333,SB_86

• Article ID: 5684
  Mohamed HE, van de Meene AML, Roberson RW, Vermaas WFJ "Myxoxanthophyll is required for normal cell wall structure and thylakoid organization in the cyanobacterium Synechocystis sp. strain PCC 6803" - Journal of Bacteriology 187(20) (2005) 6883-6892
  

  Myxoxanthophyll is a carotenoid glycoside in cyanobacteria that is of unknown biological significance. The sugar moiety of myxoxanthophyll in Synechocystis sp. strain PCC 6803 was identified as dimethyl fucose. The open reading frame sll1213 encoding a fucose synthetase orthologue was deleted to probe the role of fucose and to determine the biological significance of myxoxanthophyll in Synechocystis sp. strain PCC 6803. Upon deletion of sll1213, a pleiotropic phenotype was obtained: when propagated at 0.5 μmol photons/m2/s, photomixotrophic growth of cells lacking sll1213 was poor. When grown at 40 μmol photons/m2/s, growth was comparable to that of the wild type, but cells showed a severe reduction in or loss of the glycocalyx (S-layer). As a consequence, cells aggregated in liquid as well as on plates. At both light intensities, new carotenoid glycosides accumulated, but myxoxanthophyll was absent. New carotenoid glycosides may be a consequence of less-specific glycosylation reactions that gained prominence upon the disappearance of the native sugar moiety (fucose) of myxoxanthophy11. In the mutant, the N-storage compound cyanophycin accumulated, and the organization of thylakoid membranes was altered. Altered cell wall structure and thylakoid membrane organization and increased cyanophycin accumulation were also observed for ∆slr0940K, a strain lacking zeta-carotene desaturase and thereby all carotenoids but retaining fucose. Therefore, lack of myxoxanthophyll and not simply of fucose results in most of the phenotypic effects described here. It is concluded that myxoxanthophyll contributes significantly to the vigor of cyanobacteria, as it stabilizes thylakoid membranes and is critical for S-layer formation

  cyanobacteria, myxoxanthophyll, Synechocystis, thylakoid membrane

  NCBI PubMed ID: 16199557
  Publication DOI: 10.1128/JB.187.20.6883-6892.2005
  Journal NLM ID: 2985120R
  Publisher: American Society for Microbiology
  Correspondence: Vermaas WFJ
  Institutions: School of Life Sciences, Arizona State University, Tempe, USA
  Methods: PCR, DNA techniques, TLC, MALDI-TOF MS, HPLC, UV, extraction, affinity chromatography, cell growth, precipitation, TEM, centrifugation, optical density measurement, gene cloning, light microscopy
  
   
  
  Synechocystis sp. PCC 6803
  CSDB ID 49315 (all data & tools)