Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
NCBI PubMed ID: 7809205Publication DOI: 10.1055/s-2006-959564Journal NLM ID: 0066751Publisher: George Thieme
Institutions: Department of Pharmacy, University of Iceland, Reykjavik
A new alkali-soluble polysaccharide has been isolated from Iceland moss, Cetraria islandica (L.) Ach., by ethanol fractionation, ion-exchange chromatography, and gel filtration. The mean M(r) was estimated to be 18,000. Sugar and methylation analysis, partial hydrolysis, and 13C-NMR spectroscopy showed the polysaccharide to be a branched galactomannan with a backbone composed of two structural elements; (1-->6)-linked α-D-mannopyranosyl and α-D-(1-->6)-galactopyranosyl units. The polysaccharide showed pronounced immunostimulating activity in an in vitro phagocytosis assay and in the in in vivo carbon clearance assay.
Structure type: homopolymer
Trivial name: LAM, mannan, galactomannan, cell wall heteromannan
Compound class: EPS, O-polysaccharide, cell wall polysaccharide, N-glycan, cell surface polysaccharide, mannan, D-mannan, galactomannan
Contained glycoepitopes: IEDB_130701,IEDB_140116,IEDB_141793,IEDB_141828,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153762,IEDB_153763,IEDB_76933,IEDB_983930,SB_198,SB_44,SB_67,SB_72
Methods: phagocytosis assay, carbon clearance assay
Biosynthesis and genetic data: immunostimulating activity
Related record ID(s): 118209, 147309
NCBI Taxonomy refs (TaxIDs): 78064Reference(s) to other database(s): GTC:G55317BB, GlycomeDB:
6776, CCSD:
46066, CBank-STR:6345
Show glycosyltransferases
There is only one chemically distinct structure:
Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
NCBI PubMed ID: 7809205Publication DOI: 10.1055/s-2006-959564Journal NLM ID: 0066751Publisher: George Thieme
Institutions: Department of Pharmacy, University of Iceland, Reykjavik
A new alkali-soluble polysaccharide has been isolated from Iceland moss, Cetraria islandica (L.) Ach., by ethanol fractionation, ion-exchange chromatography, and gel filtration. The mean M(r) was estimated to be 18,000. Sugar and methylation analysis, partial hydrolysis, and 13C-NMR spectroscopy showed the polysaccharide to be a branched galactomannan with a backbone composed of two structural elements; (1-->6)-linked α-D-mannopyranosyl and α-D-(1-->6)-galactopyranosyl units. The polysaccharide showed pronounced immunostimulating activity in an in vitro phagocytosis assay and in the in in vivo carbon clearance assay.
Structure type: homopolymer
Trivial name: galactan
Compound class: EPS, CPS, galactomannan
Contained glycoepitopes: IEDB_134624,IEDB_136906,IEDB_137472,IEDB_141794,IEDB_151528,IEDB_190606,SB_163,SB_7
Methods: phagocytosis assay, carbon clearance assay
Biosynthesis and genetic data: immunostimulating activity
Comments, role: Parent molecule: galactomannan;
Related record ID(s): 147308
NCBI Taxonomy refs (TaxIDs): 78064Reference(s) to other database(s): GTC:G83948UI, CCSD:
50057, CBank-STR:4988
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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