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Structure type: oligomer
Compound class: CPS
Contained glycoepitopes: IEDB_1075132,IEDB_1075133,IEDB_120354,IEDB_130646,IEDB_130697,IEDB_135813,IEDB_136044,IEDB_136794,IEDB_137340,IEDB_137472,IEDB_137776,IEDB_1391966,IEDB_140108,IEDB_140110,IEDB_140122,IEDB_141588,IEDB_141794,IEDB_141807,IEDB_142351,IEDB_142487,IEDB_142488,IEDB_146100,IEDB_146664,IEDB_149144,IEDB_149174,IEDB_150933,IEDB_151531,IEDB_190606,IEDB_423120,IEDB_983931,SB_115,SB_116,SB_131,SB_145,SB_165,SB_166,SB_170,SB_171,SB_172,SB_173,SB_187,SB_192,SB_195,SB_30,SB_39,SB_6,SB_68,SB_7,SB_84,SB_88

• Article ID: 5806
  Li R, Yu H, Chen X "Recent progress in chemical synthesis of bacterial surface glycans" - Current Opinion in Chemical Biology 58 (2020) 121-136
  

  With the continuing advancement of carbohydrate chemical synthesis, bacterial glycomes have become increasingly attractive and accessible synthetic targets. Although bacteria also produce carbohydrate-containing secondary metabolites, our review here will cover recent chemical synthetic efforts on bacterial surface glycans. The obtained compounds are excellent candidates for the development of improved structurally defined glycoconjugate vaccines to combat bacterial infections. They are also important probes for investigating glycan–protein interactions. Glycosylation strategies applied for the formation of some challenging glycosidic bonds of various uncommon sugars in a number of recently synthesized bacterial surface glycans are highlighted.

  synthesis, carbohydrate, glycosyltransferase, glycoconjugate vaccine, Bacterial glycan

  NCBI PubMed ID: 32920523
  Publication DOI: 10.1016/j.cbpa.2020.08.003
  Journal NLM ID: 9811312
  Publisher: London: Elsevier
  Correspondence: Chen Xi
  Institutions: Department of Chemistry, University of California Davis, Davis, CA, USA
  
   
  
  Streptococcus sp. Ia
  CSDB ID 5082 (all data & tools)