Found 1 structure.
Displayed structure 1
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1. Compound ID: 15164
a-D-Manp-(1-3)-+
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a-D-Manp-(1-6)-+ | ?%D-Galp-(1-3)-+
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a-D-Manp-(1-3)-a-D-Manp-(1-6)-b-D-Manp-(1-4)-b-D-GlcpNAc-(1-4)-b-D-GlcpNAc-(1-?)-Subst-(1-2)-EtN-(1--P--6)--a-D-Manp-(1-2)-+
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a-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-GlcpNAc-(1-6)-b-D-Galp-(1-4)-b-D-GlcpNAc-(1-6)-+ |
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a-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-GlcpNAc-(1-6)-+ | | /Variants 0/-+ Ste-(1-1)-+
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a-Neup5Ac-(2-3)-b-D-Galp-(1-3)-b-D-GlcpNAc-(1-3)-b-D-Galp-(1-3)-b-D-GlcpNAc-(1-3)-b-D-Galp-(1-3)-b-D-GlcpNAc-(1-3)-b-D-Galp-(1-3)-a-D-Galp-(1-3)-a-D-Manp-(1-6)-a-D-Manp-(1-4)-a-D-GlcpN-(1-6)-myoIno-(1--P--3)--Gro
/Variants 0/ is:
Ste-(1-2)-
OR (inclusively)
Pam-(1-2)-
OR (inclusively)
C18={?}-(1-2)-
Subst = protein |
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Structure type: oligomer
Trivial name: procyclin glycoprotein
Compound class: GPI-anchor, GPI-anchored polypeptides
Contained glycoepitopes: IEDB_120354,IEDB_123886,IEDB_123890,IEDB_130646,IEDB_130701,IEDB_135813,IEDB_136044,IEDB_136104,IEDB_136794,IEDB_136906,IEDB_137340,IEDB_137472,IEDB_137485,IEDB_1391962,IEDB_140108,IEDB_140116,IEDB_140122,IEDB_141181,IEDB_141793,IEDB_141794,IEDB_141807,IEDB_141828,IEDB_141829,IEDB_142078,IEDB_143242,IEDB_143632,IEDB_143794,IEDB_144983,IEDB_144993,IEDB_146100,IEDB_149174,IEDB_150899,IEDB_150933,IEDB_151079,IEDB_151528,IEDB_151531,IEDB_152206,IEDB_153212,IEDB_153220,IEDB_153529,IEDB_157001,IEDB_158533,IEDB_164174,IEDB_187201,IEDB_190606,IEDB_241110,IEDB_241112,IEDB_423120,IEDB_429156,IEDB_474450,IEDB_534865,IEDB_548907,IEDB_857734,IEDB_983930,SB_115,SB_116,SB_127,SB_131,SB_136,SB_137,SB_156,SB_165,SB_166,SB_170,SB_171,SB_172,SB_173,SB_186,SB_187,SB_191,SB_195,SB_196,SB_197,SB_198,SB_29,SB_30,SB_33,SB_39,SB_44,SB_67,SB_68,SB_7,SB_72,SB_73,SB_74,SB_77,SB_84,SB_85,SB_88
The structure is contained in the following publication(s):
- Article ID: 5910
Cummings RD, Van Die I "Parasitic Infections" -
Book: In: Essentials of Glycobiology [Internet]. 3rd edition. (2017)
Parasitic protozoans and helminths (worms) synthesize glycans with structures often different from those typically found in vertebrates and are typically antigenic. Parasites also express glycan-binding proteins (GBPs) involved in host invasion and parasitism. As part of the disease process, parasite glycans can trigger the host's innate immune system, which can lead to the induction of adaptive immune responses. This chapter discusses the major roles of glycoconjugates in parasitic infections.
NCBI PubMed ID: 28876851Publication DOI: 10.1101/glycobiology.3e.043Publisher: Cold Spring Harbor (NY), Cold Spring Harbor Laboratory Press, 2015-2017
Correspondence: Richard D. Cummings
; Irma van Die
Editors: Varki A, Cummings RD, Esko JD
Institutions: Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA, Department of Molecular Cell Biology & Immunology, VU University Center, Amsterdam, The Netherlands
- Article ID: 6349
Cummings RD, Hokke CH, Haslam SM "Parasitic Infections" -
Book: Essentials of Glycobiology [Internet]. 4rd edition (2022)
Parasitic protozoans and helminths (worms) synthesize glycans with structures often different from those typically found in vertebrates, and are thus often antigenic. Parasites also express glycan-binding proteins (GBPs) involved in host invasion and parasitism. As part of the disease process, parasite glycans can trigger the host's innate immune system, which can lead to the induction of adaptive immune responses. This chapter discusses the major roles of glycoconjugates in parasitic infections.
NCBI PubMed ID: 35536961Publication DOI: 10.1101/glycobiology.4e.43Publisher: Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press
Correspondence: R.D. Cummings
Editors: Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Mohnen D, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger RH
Institutions: Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA, Department of Molecular Cell Biology & Immunology, VU University Center, Amsterdam, The Netherlands
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