Thaxtomin A (1) and B (2), the two major phytotoxins associated with the common scab of potato disease, were transformed into C-14 linked β-glucosides (3) and (4), respectively, when individually incubated with cultures of Bacillus mycoides in oatmeal broth at 26 °C. These biotransformation products when assayed on aseptically produced potato minitubers proved to be much less phytotoxic than the parent compounds.
glucosylation, thaxtomin A, phytotoxins, detoxification, Streptomyces scabies, Bacillus mycoides
NCBI PubMed ID: 10691667Publication DOI: 10.1021/jf990912oJournal NLM ID: 0374755Publisher: American Chemical Society
Institutions: Agriculture and Agri-Food Canada, Potato Research Centre, Fredericton, Canada, Department of Chemistry, University of New Brunswick, Fredericton, Canada
Methods: 13C NMR, 1H NMR, FAB-MS, TLC, acid hydrolysis, HPLC, extraction, cell growth, phytotoxicity assay
Found