Found 1 structure.
Displayed structure 1
Expand all compounds
Collapse all compounds
Show all as text (SweetDB notation)
Show all graphically (SNFG notation)
1. Compound ID: 1750
|
a-L-Fucp-(1-2)-+
|
-2)-b-D-Manp-(1-3)-b-D-Galp-(1-3)-a-D-GlcpNAc-(1-3)-b-D-GlcpNAc-(1- |
Show graphically |
Structure type: polymer biological repeating unit
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_135813,IEDB_136044,IEDB_136045,IEDB_137340,IEDB_137472,IEDB_137485,IEDB_141794,IEDB_141807,IEDB_142489,IEDB_144562,IEDB_144983,IEDB_149554,IEDB_150899,IEDB_150948,IEDB_151531,IEDB_152206,IEDB_152214,IEDB_153553,IEDB_174333,IEDB_190606,IEDB_461719,IEDB_983930,SB_100,SB_137,SB_154,SB_165,SB_166,SB_187,SB_195,SB_29,SB_44,SB_7,SB_72,SB_86,SB_88
The structure is contained in the following publication(s):
- Article ID: 540
Larsson EA, Urbina F, Yang Z, Weintraub A, Widmalm G "Structural and immunochemical relationship between the O-antigenic polysaccharides from the enteroaggregative Escherichia coli strain 396/C-1 and Escherichia coli O126" -
Carbohydrate Research 339(8) (2004) 1491-1496
The structure of the O-antigen polysaccharide (PS) from the enteroaggregative Escherichia coli strain 396/C-1 has been determined. Sugar and methylation analyses together with (1)H and (13)C NMR spectroscopy were the main methods used. Inter-residue correlations were determined by (1)H,(1)H-NOESY, (1)H,(13)C-heteronuclear multiple-bond correlation and dipole-dipole cross-correlated relaxation experiments. The PS is composed of pentasaccharide repeating units with the following structure: Analysis of NMR data reveals that on average the PS consists of approximately 13 repeating units and indicates that the biological repeating unit contains an N-acetylglucosamine residue at its reducing end. This structure is different to that reported for the O-antigen polysaccharide from E. coli O126. Monospecific anti-E. coli O126 rabbit serum from The International Escherichia and Klebsiella Centre did not distinguish between the E. coli strain 396/C-1 and the E. coli O126 reference strain, neither in slide agglutination nor in an indirect enzyme immunoassay. Subsequent successful serotyping of the E. coli strain 396/C-1 showed it to be E. coli O126:K+:H27.
Lipopolysaccharide, NMR, Escherichia coli, serology, Enteroaggregative
NCBI PubMed ID: 15178392Publication DOI: 10.1016/j.carres.2004.04.002Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: G. Widmalm
Institutions: Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden
Methods: methylation, NMR-2D, NMR, sugar analysis
Expand this compound
Collapse this compound
Total list of structure IDs on all result pages of the current query:
Total list of corresponding CSDB IDs (permanent record IDs):
Execution: <1 sec