Reactions between water-insoluble and water-soluble components are often slow, giving low yields. In order to prepare glycolipids composed of polysialic acid and N-(4-(p-maleimidylphenyl)butyryl)dipalmitoyl-L-α-phosphatidylethanol amine triethylammonium salt, we used liposomes to enhance the interfacial reaction between the reagents. Thus, thiolreactive liposomes were reacted with polysialic acid cysteamine. A 70% yield was achieved with this addition reaction, and the product was isolated by dialysis and centrifugation.

• Compound ID: 4436
  

  -8)-a-Neup5Ac-(2-8)-a-Neup5Ac-(2-

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  Structure type: polymer chemical repeating unit
  Trivial name: colominic acid, Japanese common char (Salvelinus leucomaenis pluvius)
  Compound class: CPS, O-glycoprotein, polysialate
  Reference(s) to other database(s): GTC:G74009LP, GlycomeDB:660
  
   
  
  Escherichia coli
  CSDB ID 111111 (all data & tools)