Five cerebrosides (1-5), including three new ones named cortenuamide A (1), cortenuamide B (2), and cortenuamide C (3), were isolated from the fruiting bodies of the basidiomycete Cortinarius tenuipes. The structures of those compounds were elucidated as (4E,8E)-N-D-2′-hydroxytetracosanoyl-1-O-β-D-glycopyranosyl-9-methyl-4,8-sphingadienine (1), (4E,8E)-N-D-2′-hydroxytricosanoyl-1-O-β-D-glycopyranosyl-9-methyl-4,8-sphingadienine (2), (4E,8E)-N-D-2′-hydroxydocosanoyl-1-O-β-D-glycopyranosyl-9-methyl-4,8-sphingadienine (3), (4E,8E)-N-D-2′-hydroxyoctadecanoyl-1-O-β-D-glycopyranosyl-9-methyl-4,8-sphingadienine (4), and (4E,8E)-N-D-2′-hydroxypalmitoyl-1-O-β-D-glycopyranosyl-9-methyl-4,8-sphingadienine (5) by spectral and chemical methods.
cerebrosides, Cortinarius tenuipes, cortenuamides
NCBI PubMed ID: 12669823Publication DOI: 10.1007/s11745-003-1034-8Journal NLM ID: 0060450Publisher: American Oil Chemists' Society
Correspondence: Liu JK
Institutions: Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming, China
Methods: 13C NMR, 1H NMR, EI-MS, NMR-2D, IR, FAB-MS, GC-MS, TLC, acid hydrolysis, MS, methanolysis, extraction, optical rotation measurement, CC, reversed-phase chromatography, melting point determination
Found