Peniciside, a new fernene triterpenoid glycoside, was isolated from the EtOAc extract of the solid-state fermented rice culture of the fungus Penicillium sp. 169. Its structure was elucidated on the basis of spectroscopic analysis, and the absolute configuration was determined by X-ray crystallographic analysis and chemical methods. Peniciside is the first example of a fernene triterpenoid glycoside with two hydroxyls at C-19 and C-20.
metabolite, fungus, Penicillium, peniciside, solid-state fermentation, triterpenoid glycoside
NCBI PubMed ID: 22370784Publication DOI: 10.1007/s12272-012-0210-zJournal NLM ID: 8000036Publisher: Pharmaceutical Society of Korea
Correspondence: Li GY
; Yang T
Institutions: College of Life Sciences and Engineering, Southwest University of Science and Technology, Mianyang, China, Key Laboratory of Environmental and Applied Microbiology, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China
Methods: 13C NMR, 1H NMR, IR, X-ray, TLC, ESI-MS, acid hydrolysis, extraction, optical rotation measurement, CC, cell growth, HR-ESI-MS, evaporation
Found