Microbial transformation of psiadiarabin and its 6-desmethoxy analogue 5,3′ dihydroxy-7,2′,4′,5′-tetramethoxyflavone by Cunninghamella elegans NRRL 1392 gave the 3′-glucoside conjugates of the two flavones. Structural elucidation of these two new metabolites was achieved using 1D and 2D NMR spectroscopy and CIMS.
5, biotransformation, Cunninghamella elegans, Psiadia arabica, compositae, psiadiarabin, 3′-dihydroxy-7, 2′, 4′, 5′-tetramethoxyflavone, glucoside conjugates
Publication DOI: 10.1016/S0031-9422(97)80010-6Journal NLM ID: 0151434Publisher: Elsevier
Institutions: Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
Methods: 13C NMR, 1H NMR, ESI-MS, extraction, optical rotation measurement, CC, melting point determination