Two new compounds isolated from an extract of a Central Asian lichen [Umbilicaria proboscidea (L.) Schrader=Syn.: Gyrophora proboscidea (L.) Ach.] are glucosides with mono- and di-prenylated xanthones as the aglycones and a saccharide moiety from two glucoses linked at C-7. The structures were elucidated on the basis of extensive spectroscopic analysis (1D and 2D NMR, MS, IR and UV) and by hydrolysis
lichen, Umbilicaria proboscidea, prenylated xanthones, xanthone glucosides
NCBI PubMed ID: 12560034Publication DOI: 10.1016/s0031-9422(02)00539-3Journal NLM ID: 0151434Publisher: Elsevier
Correspondence: Rezanka T
Institutions: Institute of Microbiology, Prague, Czech, Department of Pharmaceutical Chemistry and Natural Products School of Pharmacy, Hebrew University of Jerusalem, Jerusalem, Israel
Methods: 13C NMR, 1H NMR, gel filtration, NMR-2D, IR, FAB-MS, acid hydrolysis, GC, UV, enzymatic digestion, extraction, optical rotation measurement, RP-HPLC, melting point determination, derivatization, HR-FAB-MS