Show legend Show as text

Structure type: structural motif or average structure ; 15300
Compound class: glucogalactan
Contained glycoepitopes: IEDB_135614,IEDB_136906,IEDB_137472,IEDB_140529,IEDB_141794,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_151528,IEDB_153543,IEDB_167069,IEDB_190606,IEDB_241101,IEDB_983931,SB_192,SB_7

• Article ID: 8767
  Siu KC, Xu L, Chen X, Wu JY "Molecular properties and antioxidant activities of polysaccharides isolated from alkaline extract of wild Armillaria ostoyae mushrooms" - Carbohydrate Polymers 137 (2016) 739-746
  

  This study aims to discover novel and bioactive polysaccharides (PS) from wild Armillaria ostoyae, a honey mushroom species. Two PS designated AkPS1V-1 (66.6 kDa) and AkPS1V-2 (15.3 kDa) were isolated and fractionated by anion ion exchange (IEC) and size exclusion chromatography (SEC) from the alkaline extract of A. ostoyae mushrooms. AkPS1V-1 was a glucan composed of solely glucose residues and AkPS1V-2 a heteropolysaccharide composed of glucose and galactose at 6:1 molar ratio. AkPS1V-2 exhibited higher antioxidant activities than AkPS1V-1 based on reducing power, radical scavenging and metal chelating assays. The structure of AkPS1V-2 was further analyzed and elucidated as a branched galactoglucan with a backbone composed of (1→6)-β-D-glucopyranosyl, (1→3)-β-D-glucopyranosyl, (1→3)-α-D-galactopyranosyl and (1→3,6)-β-D-glucopyranosyl residues at 3:1:1:1 ratio, and side chain of (1→3)-β-D-glucopyranosyl residue. This is the first report on a pure PS structure and its antioxidant activities from this mushroom species.

  structure, polysaccharides, extraction, Antioxidant activity, Fractionation, Armillaria ostoyae

  NCBI PubMed ID: 26686187
  Publication DOI: 10.1016/j.carbpol.2015.05.061
  Journal NLM ID: 8307156
  Publisher: Elsevier
  Correspondence: Wu JY
  Institutions: Department of Applied Biology & Chemical Technology, State Key Laboratory of Chinese Medicine and Molecular Pharmacology in Shenzhen, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, College of Agricultural Resource and Environment, Heilongjiang University, Harbin, China
  Methods: 13C NMR, 1H NMR, GC-MS, FTIR, HPLC, viscosity measurement, acetylation, statistical analysis, methylation analysis, SEC, reduction with NaBH4, antioxidant activities, HPGPC, HMBC, radical scavenging assay, TFA hydrolysis
  
   
  
  Armillaria ostoyae
  CSDB ID 42894 (all data & tools)

Show legend Show as text

Structure type: structural motif or average structure
Compound class: polysaccharide, galactoglucan
Contained glycoepitopes: IEDB_136044,IEDB_137472,IEDB_141794,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_153218,IEDB_190606,IEDB_241101,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_7,SB_88

• Article ID: 9709
  Liu JJ, Hou YK, Wang X, Zhou XT, Yin JY, Nie SP "Recent advances in the biosynthesis of fungal glucan structural diversity" - Carbohydrate Polymers 329 (2024) ID 121782
  

  Glucans are the most abundant class of macromolecule polymers in fungi, which are commonly found in Ascomycota and Basidiomycota. Fungal glucans are not only essential for cell integrity and function but also crucial for the immense industrial interest in high value applications. They present a variety of structural characteristics at the nanoscale due to the high regulation of genes and the involvement of stochastic processes in synthesis. However, although recent findings have demonstrated the genes of glucans synthesis are relatively conserved across diverse fungi, the formation and organization of diverse glucan structures is still unclear in fungi. Here, we summarize the structural features of fungal glucans and the recent developments in the mechanisms of glucans biosynthesis. Furthermore, we propose the engineering strategies of targeted glucan synthesis and point out the remaining challenges in the synthetic process. Understanding the synthesis process of diverse glucans is necessary for tailoring high value glucan towards specific applications. This engineering strategy contributes to enable the sustainable and efficient production of glucan diversity

  biosynthesis, gene, diversity, glucan, fungi, target glucan

  NCBI PubMed ID: 38286552
  Publication DOI: 10.1016/j.carbpol.2024.121782
  Journal NLM ID: 8307156
  Publisher: Elsevier
  Correspondence: Yin JY ; Nie SP
  Institutions: State Key Laboratory of Food Science and Resources, China-Canada Joint Lab of Food Science and Technology (Nanchang), Nanchang University, Nanchang, China, Food Laboratory of Zhongyuan, Henan, China
  
   
  
  Armillaria ostoyae
  CSDB ID 41580 (all data & tools)