A new 9,10-dihydrophenanthrene derivative named epimedoicarisoside A was isolated from the aerial parts of Epimedium koreanum along with ten known flavonoids. The structure of this compound was determined on the basis of spectral analysis (FAB-Mass spectrometry, 1H-1H COSY, 13C COSY, DEPT, and 13C long range COSY, etc.) as 2-hydroxy-3,4,6,7-tetramethoxy-9,10-dihydrophenanthrene-2-O-β-D-glucopyranoside. The known compounds were identified as icariin, epimedoside C, icarisid I, baohuoside I, diphylloside A, baohuoside II, 2″-O-rhamnosylicarisid II, sagittatoside A, hyperoside and icaritin-3-O-rhamnopyranoside.
flavonoids, Epimedium koreanum, Berberidaceae, 9, 10-dihydrophenanthrene derivate, epimedoicarisoside A, icariin, epimedoside C, icarisid I, baohuoside I, diphylloside A, baohuoside II, 2″-O-rhamnosylicarisid II, sagittatoside A, hyperoside, icaritin-3-O-rhamnopyranoside
Publication DOI: 10.1016/0031-9422(94)00926-KJournal NLM ID: 0151434Publisher: Elsevier
Institutions: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, Department of Chemistry, Peking University, Beijing, China, Department of Phytochemistry, School of Pharmaceutical Sciences, Beijing Medical University, Beijing, China
Methods: 13C NMR, 1H NMR, NMR-2D, IR, FAB-MS, TLC, UV, extraction, CC, melting point determination, recrystallization
Found