A New phenylethanoid glycoside, named tubuloside E (I), and a new neolignan glycoside, dehydrodiconiferyl alcohol γ'-O-β-D-glucopyranoside (II), were isolated from the whole plants of Cistanche tubulosa (SCHRENK)HOOK. f. (Orobanchaceae), together with dehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside (III), syringalide A 3'-α-L-rhamnopyranoside (IV), isosyringalide 3'-α-L-rhamnopyranoside (V), (+)-syringaresinol O-β-D-glucopyranoside (VI), (+)-pinoresinol O-β-D-glucopyranoside (VII), liriodendrin (VIII), 6-deoxycatalpol (IX), 8-epiloganic acid (X), 20-hydroxyecdysone (XI), 8-hydroxygeraniol 1-β-D-glucopyranoside (XII) and syringin (XIII). The structure of tubuloside E (I) was established as 2-(3, 4-dihydroxyphenyl)ethyl O-α-L-rhamnopyranosyl-(1→3)-2-O-acetyl-4-O-p-coumaroyl-β-D-glucopyranoside on the basis of chemical evidence and spectral data.
13C-NMR, Cistanche tubulosa, Orobanchaceae, phenylethanoid glycoside, iridoid, tubuloside E, dehydrodiconiferyl alcohol glycoside, syringalide rhamnoside, neolignan glycoside
Publication DOI: 10.1248/cpb.38.1927Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Central Research Laboratories, Yomeishu Seizo Co., Ltd., Minowa, Japan, Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan
Methods: 13C NMR, 1H NMR, IR, TLC, acid hydrolysis, GC, methanolysis, HPLC, UV, enzymatic digestion, extraction, optical rotation measurement, acetylation, CD, elemental analysis, reduction, CC, melting point determination
Found