Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
NCBI PubMed ID: 18415016Journal NLM ID: 8603310Publisher: Kluwer Academic Publishers
Correspondence: akmisra69
rediffmail.com
Institutions: Medicinal and Process Chemistry Division, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, 226 001, India
A block synthetic approach is presented for the synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O83:K24:H31 strain, present in the 'Colifant' vaccine. The target pentasaccharide has been synthesized by coupling a disaccharide with a trisaccharide in excellent yield. Yields are quite satisfactory in all intermediate steps
synthesis, O-antigen, repeating unit, Escherichia coli, pentasaccharide
Structure type: suggested polymer biological repeating unit
Location inside paper: p.714, fig. 1
Compound class: O-polysaccharide, O-antigen, LPS
Contained glycoepitopes: IEDB_115136,IEDB_130646,IEDB_135813,IEDB_136044,IEDB_137340,IEDB_137472,IEDB_140108,IEDB_140122,IEDB_140630,IEDB_141794,IEDB_141807,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_151531,IEDB_190606,IEDB_221845,IEDB_423153,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_30,SB_7,SB_88
Methods: 13C NMR, 1H NMR, NMR-2D, chemical methods, NMR-1D, glycosylation
Synthetic data: chemical
Comments, role: chemical repeat frame is different in the paper
Related record ID(s): 20700, 22426, 23124, 26494
NCBI Taxonomy refs (TaxIDs): 2079164Reference(s) to other database(s): GTC:G51834NG, GlycomeDB:
36874, CCSD:
33512, CBank-STR:13736
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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