Two new cerebrosides, asperiamide B (1) and C (2), and two known aflatoxins, averufin and nidurufin, have been isolated from a Quanzhou marine fungus Aspergillus niger (MF-16), and the structures were elucidated by spectroscopic data and chemical means. Among the compounds 5 and 6 showed moderate activities in inhibiting multiplication of the Tobacco Mosaic Virus (TMV).
anthraquinone, cerebroside, Aspergillus niger, Marine fungus, asperiamide B, asperiamide C
Publication DOI: 10.1002/cjoc.200890142Journal NLM ID: 101312673Publisher: Beijing, China: Science Press
Correspondence: maouyang@yahoo.com
Institutions: Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China, Education Ministry, Key Laboratory of Bio-pesticide and Chemistry-Biology, Fujian Agriculture and Forestry University, Fuzhou, China, Department of Chemistry, National Taiwan University, Taipei, China
Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, ELISA, acid hydrolysis, biological assays, UV, extraction, optical rotation measurement, HPTLC, CC, cell growth, evaporation, HR-FAB-MS