Two new sesquiterpenoids, 1-2, together with three known compounds, were isolated from Trichoderma hypoxylon. Among the known compounds, compound 4 was isolated as naturally occurring compound for the first time. The structures of these new compounds were characterized by HR-ESI-MS and spectroscopic methods including 1D and 2D NMR. The absolute configurations of 1-2 were assigned by electronic circular dichroism (ECD) calculations.
glycoside, fungi, Trichoderma, rearranged cuparane, sesquiterpenes
NCBI PubMed ID: 35186411Publication DOI: 10.1080/21501203.2021.1964630Journal NLM ID: 101523848Publisher: Abingdon, Oxon: Taylor & Francis
Correspondence: Wen-Bing Yin
Institutions: State Key Laboratory Of Mycology, Institute Of Microbiology, Chinese Academy Of Sciences, Beijing, Republic of China, University Of Chinese Academy Of Sciences, Beijing, Republic of China
Methods: 13C NMR, 1H NMR, NMR-2D, IR, acid hydrolysis, HPLC, extraction, optical rotation measurement, fermentation, HR-ESI-MS, ECD, silica gel chromatography, identification
Found