A systematic separation of a saponin fraction of the root of Bupleurum falcatum L. furnished seven new saponins, i.e., five monoacetylsaikosaponins (15-18,20) and saikosaponins-e (19) and -f (21), besides the known saikosaponins-a, -b2,-b4,-c, and -d. α-Spinasteryl β-D-glucoside (22) was also isolated. The structures of these new saponins were determined by means of carbon-13 nuclear magnetic resonance spectroscopy.
13C NMR spectroscopy, Bupleurum falcatum, separation of saikosaponins, saikogenins A-G, saikosaponin-a, saikosaponin-b1, saikosaponin-b2, saikosaponin-b3, saikosaponin-b4, saikosaponin-c, saikosaponin-d, saikosaponin-e, saikosaponin-f, monoacetylsaikosaponin, α-spinasteryl β-D-glucoside, acetylation shift
Journal NLM ID: 0377775WWW link: http://ci.nii.ac.jp/naid/110003624035Publisher: Pharmaceutical Society Of Japan
Institutions: Shionogi Research Laboratory, Shionogi and Co, Japan
Methods: 13C NMR, 1H NMR, TLC, melting point determination, acetylation analysis
Found