Show legend Show as text

Structure type: oligomer
Trivial name: balanitin 2
Compound class: saponin glycoside
Contained glycoepitopes: IEDB_114701,IEDB_136105,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_167188,IEDB_174332,IEDB_225177,IEDB_885823,IEDB_983931,SB_192

• Article ID: 9827
  Liu HW, Nakanishi K "A micromethod for determining the branching points in oligosaccharides based on circular dichroism" - Journal of the American Chemical Society 103 (1981) 7005-7006
  
  Publication DOI: 10.1021/ja00413a057
  Journal NLM ID: 7503056
  Publisher: American Chemical Society
  Institutions: Department of Chemistry, Columbia University, New York, New York, USA
  Methods: TLC, acid hydrolysis, methanolysis, CI-MS, CD, Hakomori method
  
   
  
  Balanites aegyptiaca
  CSDB ID 131383 (all data & tools)

Show legend Show as text

Structure type: oligomer
Trivial name: balanitin 7
Compound class: triterpenoid glycoside
Contained glycoepitopes: IEDB_114701,IEDB_136105,IEDB_142488,IEDB_146664,IEDB_167188,IEDB_174332,IEDB_225177,IEDB_885823,IEDB_983931,SB_192

• Article ID: 11394
  Deng SJ, Yu B, Hui YZ "A facile synthetic approach to a group of structurally typical diosgenyl saponins" - Tetrahedron Letters 39(36) (1998) 6511-6514
  

  Five new steroids, the cholest-4-ene-3,22-diones : tumacone A (1), tumacone B (2), tumacoside A (3), tumacoside B (4), and a furostenone: tumaquenone (5), besides diosgenone (6), were isolated from the aerial parts of Solanum nudum. Their structures were determined by 2D NMR, MS analyses and chemical correlations. Steroid 3 and 5 displayed in vitro antimalarial activity against a Plasmodium falciparum chloroquine-resistant FCB-1 strain (IC50 27 and 16 mu M). The observed stereodependent cyclization into spiroketals of two 16-O isomers is discussed.

  antimalarial, steroids, Solanum nudum, cholest-4-en-3, 22-dione, tumacones A and B, tumacosides A and B, tumaquenone, stereodependent cyclization

  Publication DOI: 10.1016/S0040-4039(98)01354-9
  Journal NLM ID: 2984819R
  Publisher: Elsevier
  Institutions: State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China
  Methods: 13C NMR, 1H NMR, EI-MS, IR, optical rotation measurement, CC, NOESY, HR-FAB-MS, extraciton
  
   
  
  Balanites aegyptica
  CSDB ID 61593 (all data & tools)