Following the structure elucidation of licorice-saponins A3,B2,C2,D3,and E2,the structures of five more new oleanene-triterpene oligoglycosides named licorice-saponins F3 (1), G2 (5), H2 (7), J2 (10), and K2 (12), concomitantly isolated from the root of Glycyrrhiza uralensis Fischer= (Tohoku-kanzo in Japanese), have been determined on the basis of chemical and physicochemical evidence. During the process, a facile chemical conversion method from olean-12-ene or olean-12-en-11-one oligoglycosides to an olean-11,13-diene oligoglycoside, has been found.
Glycyrrhiza uralensis, Glycyrrhiza Radix, licorice-saponin F3, licorice-saponin G2, licorice-saponin H2, licorice-saponin J2, licorice-saponin K2, olean-11, 13-diene olygoglycoside
Publication DOI: 10.1248/cpb.39.244Journal NLM ID: 0377775WWW link: http://ci.nii.ac.jp/naid/110003628898Publisher: Pharmaceutical Society Of Japan
Institutions: Faculty of Pharmaceutical Sciences, Osaka University, Osaka, japan
Methods: 13C NMR, 1H NMR, IR, methanolysis, methylation analysis, Fab-MS
Found