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Structure type: oligomer
Trivial name: causiaroside II
Compound class: saponin glycoside
Contained glycoepitopes: IEDB_136105,IEDB_142488,IEDB_146664,IEDB_225177,IEDB_885823,IEDB_983931,SB_192

• Article ID: 10047
  Idaka K, Hirai Y, Shoji J "Studies on the constituents of Palmae plants. IV. the constituents of the leaves of Sabal causiarum Becc" - Chemical and Pharmaceutical Bulletin 36 (1988) 1783-1790
  

  The constituents of the leaves of Sabal causiarum BECC. have been investigated. Vitexin, methyl proto-deltonin, methyl proto-causiaroside I(=26-O-β-D-glucopyranosyl 22-O-methyl-25(R)-furost-5-en-3β,26-diol 3-O-[α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→4)][α-L-rhamnopyranosyl(1→2)]-β-D-glucopyranoside) and causiaroside II(=3β,16β-dihydroxypregn-5-en-20-one 3-O-[α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosy(1→4)][α-L-rhamnopyranosyl(1→2)]-β-D-glucopyranosyl 16-O-[δ-(β-D-glucopyranosyloxy)-γ-methyl]-valerate) were isolated and identified. This is the first isolation and characterization of the latter two compounds from a natural source, and these results are interesting from the standpoint of the biogenesis of the steroidal glycosides of the Palmae plants.

  steroidal saponin, Palmae, Sabal causiarum, methyl proto-deltonin, methyl proto-causiaroside I, causiaroside II, 20, 22-secofurostanol, C-glycosyl flavonoid, vitexin

  Journal NLM ID: 0377775
  WWW link: http://ci.nii.ac.jp/naid/110003626991
  Publisher: Pharmaceutical Society Of Japan
  Institutions: School of Pharmaceutical Sciences, Showa University, Japan
  Methods: 13C NMR, 1H NMR, gel filtration, IR, TLC, acid hydrolysis, GLC, methanolysis, enzymatic digestion, partial methanolysis, methylation analysis, melting point determination, acetylation analysis
  
   
  
  Sabal causiarum
  CSDB ID 269440 (all data & tools)

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Structure type: oligomer ; 1085.5186 [M+Na]+
C₅₁H₈₂O₂₃
Trivial name: hypoglaucin G
Compound class: saponin glycoside
Contained glycoepitopes: IEDB_136105,IEDB_142488,IEDB_146664,IEDB_225177,IEDB_885823,IEDB_983931,SB_192

• Article ID: 11855
  Hu K, Yao XS, Dong AJ, Kobayashi H, Iwasaki S, Jing YK "A new pregnane glycoside from Dioscorea collettii var. hypoglauca" - Journal of Natural Products 62(2) (1999) 299-301
  

  During further bioactivity-guided fractionation, a new pregnane glycoside, hypoglaucin G (1), and a known compound, pregna-5,16-dien-3β-ol-20-one 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]β-D-glucopyranoside (2), were isolated from the EtOH extract of Dioscorea collettii vat. hypoglauca rhizomes, which induced morphological deformation of Pyricularia oryzae mycelia with minimum morphological deformation concentration values of 135 μM and 236 μM, respectively. The structure of 1 was established as 16β-(4'-methyl-5'-O-β-D-glucopyranosyl-pentanoxyl)-pregn-5-en-3β-ol-20-one 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-giucopyranoside on the basis of chemical evidence and spectral analysis, especially by 2D NMR techniques.

  pregnane glycoside, Dioscorea collettii var. hypoglauca, hypoglaucin G

  NCBI PubMed ID: 10075765
  Publication DOI: 10.1021/np980101z
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: Jing YK
  Institutions: Department of Natural Products Chemistry, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110015, China, Institute of Drug Research and Development, Northeast Pharmaceutical Corp., 37 Zhonggong Beijie, Shenyang 110026, China, Institute of Molecular & Cellular Biosciences, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113, Japan, Department of Medicine, Mount Sinai School of Medicine, Box 1178, One Gustave L. Levy Place, New York, New York 10029, USA
  Methods: 13C NMR, 1H NMR, IR, TLC, GC, HPLC, optical rotation measurement, cytotoxicity assay, HMBC, HMQC, DEPT, COSY, antifungal activity test, HRMS, sulfuric acid hydrolysis, trimethylsilylation
  
   
  
  Dioscorea collettii var. hypoglauca
  CSDB ID 63257 (all data & tools)