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Structure type: oligomer
Compound class: saponin glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192

• Article ID: 10078
  Abe F, Mori Y, Yamauchi T "Cardenolide glycosides from the seeds of Asclepias curassavica" - Chemical and Pharmaceutical Bulletin 40(11) (1992) 2917-2920
  

  From the seeds of Asclepias curassavica, two cardenolides and twelve glycosides were obtained. Among these, four compounds were determined to be 16α-hydroxycalotropagenin, 16α-hydroxycalotropin and its 3'-O-glucoside and 3'-O-gentiobioside. Normally linked triosides of corotoxigenin, coroglaucigenin and 12β-hydroxycoroglaucigenin were characterized as cellobiosyl-allomethylosides.

  Asclepias curassavica, seed cardenolide, 12β-hydroxy-coroglaucigenin, 4'-O-cellobiosyl-12β-hydroxyfrugoside, 4'-O-cellobiosyl-gofruside, doubly linked cardenolide glycoside, 16α-hydroxy-calotropagenin, 3'-O-gentiobiosyl-16α-hydroxy-calotropin

  Publication DOI: 10.1248/cpb.40.2917
  Journal NLM ID: 0377775
  Publisher: Pharmaceutical Society Of Japan
  Institutions: Faculty of Pharmaceutical Sciences, Fukuoka University, Japan
  Methods: FAB-MS, NMR
  
   
  
  Asclepias curassavica
  CSDB ID 120044 (all data & tools)

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Structure type: monomer ; 624.2244 [M+Na]+
C₃₅H₃₉NO₉S
Compound class: glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192

• Article ID: 11969
  Abe F, Yamauchi T "An androstane bioside and 3'-thiazolidinone derivatives of doubly-linked cardenolide glycosides from the roots of Asclepias tuberosa" - Chemical and Pharmaceutical Bulletin 48(7) (2000) 991-993
  

  Steroidal compounds in the roots of Asclepias tuberosa were investigated and 17α-hydroxyandrosta-4,6,15-trien-3-one 17-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside, termed ascandroside, was isolated from the CHCl3-soluble fraction. Among five doubly-linked cardenolide glycosides, two were identified as 3'-spiro-linked thiazolidinone (4) and S-oxythiazolidinone derivatives (5) of Δ5-calotropin. The stereochemistry at the C-3' in these two cardenolides is discussed. 3'-O-β-D-glucopyranosyl-Δ5-calotropin (3) was also isolated along with Δ5-calotropin and its 3'-acetate. Nine glycosides of uzarigenin, coroglaucigenin and corotoxigenin were identified.

  Asclepias tuberosa, androstane bioside, thiazolidinone-linked Δ5-calotropin, pleurisy root

  NCBI PubMed ID: 10923828
  Publication DOI: 10.1248/cpb.48.991
  Journal NLM ID: 0377775
  Publisher: Pharmaceutical Society Of Japan
  Correspondence: abefumi@fukuoka-u.ac.jp
  Institutions: Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan
  Methods: 13C NMR, 1H NMR, IR, acid hydrolysis, GC, HPLC, UV, extraction, optical rotation measurement, CC, melting point determination, derivatization, HR-FAB-MS
  
   
  
  Asclepias tuberosa
  CSDB ID 64554 (all data & tools)