Phytochemical examination of the fresh bulbs of Allium schubertii led to the isolation of four new steroidal saponins together with a known saponin. The structures of the new saponins were established by spectroscopic data, hydrolysis and chemical correlation as (25R and S)-5α-spirostan-2α,3β,6β-triol 3-O-β-d-glucopyranosyl-(1→2)-O-[4-O-benzoyl-β-d-xylopyranosyl-(1→3)]-O-β-d-glucopyranosyl-(1→4)-β-d-galactopyranoside, (25R and S)-5α-spirostan-2α,3β,6β-triol 3-O-β-d-glucopyranosyl-(1→2)-O-[3-O-benzoyl-β-d-xylopyranosyl-(1→3)]-O-β-d-glu-copyranosyl-(1→4)-β-d-galactopyranoside, (25R and S)-5α-spirostan-2α,3β,6β-triol 3-O-β-d-glucopyranosyl-(1→2)-O-[4-O-(3S)-3-hydroxy-3-methylglutaroyl-β-d-xylopyranosyl-(1→3)]-O-β-d-glucopyranosyl-(1→4)-β-d-galactopyranoside and 26-O-β-d-glucopyranosyl-(25R and S)-5α-furostan-2α,3β,6β,22ξ,26-pentol 3-O-β-d-glucopyranosyl-(1→2)-O-[β-d-xylopyranosyl-(1→3)]-O-β-d-glucopyranosyl-(1→4)-β-d-galactopyranoside, respectively.
steroidal saponins, furostanol saponin, Allium schubertii, Liliaccae, bulbs, spirostanol saponins, aginoside, turoside A, benzoic acid esters, 3-hydroxy-3-methylglutaric acid ester
NCBI PubMed ID: 7763477Publication DOI: 10.1016/S0031-9422(00)95103-3Journal NLM ID: 0151434Publisher: Elsevier
Institutions: Tokyo College of Pharmacy, Japan
Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, methanolysis, HPLC, alkaline hydrolysis, enzymatic digestion, methylation analysis
Found