A new triterpene saponin, gymnocladus saponin D (5), having a glycosyl monoterpene carboxylate and a monoterpene carboxylate group, was isolated and its structure was characterized as the (6S)-2-trans-2,6-dimethyl-6-hydroxy-2,7-octadienoate of 2β,23-dihydroxy-3-O-α-L-rhamno-pyranosyl-21-O-[(6S)-2-trans-2,6-dimethyl-6-α-L-arabinopyranosyloxy-2,7-octadienoyl]-acacic acid 28-O-β-D-xylopyranosyl-(1→3)-β-D-xylopyranosyl-(1→2)-[L-rhamnopyranosyl-(1→6)]-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside, on the basis of chemical and physicochemical evidence.
13C NMR, triterpenoid, saponin, Leguminosae, Gymnocladus chinensis, gymnocladus saponin D, 2β, 23-dihydroxy-acacic acid lactone, monoterpene acid, monoterpene glycoside
Publication DOI: 10.1248/cpb.33.4732Journal NLM ID: 0377775WWW link: http://ci.nii.ac.jp/naid/110003625251Publisher: Pharmaceutical Society Of Japan
Institutions: Kyoto Pharmaceutical University, Kyoto, Japan, Daiichi College of Pharmaceutical Sciences, Fukuoka, Japan
Methods: 13C NMR, 1H NMR, TLC, GLC, methanolysis, alkaline hydrolysis, UV, partial methanolysis, reduction, permethylation analysis, acetylation analysis
Found