Show legend Show as text

Structure type: oligomer
Trivial name: proto-dioscin
Compound class: saponin glycoside, triterpenoid glycoside
Contained glycoepitopes: IEDB_136105,IEDB_142488,IEDB_146664,IEDB_225177,IEDB_885823,IEDB_983931,SB_192

• Article ID: 10461
  Tal B, Tamir I, Rokem JS, Goldberg I "Isolation and characterization of an intermediate steroid metabolite in diosgenin biosynthesis in suspension cultures of Dioscorea deltoidea cells" - Biochemical Journal 219(2) (1984) 619-624
  

  The aglycon form of the steroidal sapogenin furost-5-ene-3β,22,26-triol, 3β-chacotrioside 26 β-D-glucopyranoside was isolated from cell suspension cultures of Dioscorea deltoidea and its molecular structure was determined by mass spectrometry and 1H and 13C n.m.r. spectroscopy. From kinetic studies and incorporation experiments with [1-14C]acetate it was concluded that the steroidal compound (in the glycoside form) is an intermediate in vivo in diosgenin biosynthesis. It accumulated in growing cells of D. deltoidea and was metabolized to diosgenin (in the glycoside form, i.e. dioscin ) in non-dividing cells.

  NCBI PubMed ID: 6547599
  Publication DOI: 10.1042/bj2190619
  Journal NLM ID: 2984726R
  Publisher: London, UK : Published by Portland Press on behalf of the Biochemical Society
  Institutions: Department of Applied Microbiology, The Hebrew University, Jerusalem, Israel, The Fermentation Unit, The Hebrew University, Jerusalem, Israel
  
   
  
  Dioscorea deltoidea
  CSDB ID 105961 (all data & tools)
• Article ID: 11534
  Ahmad VU, Khaliq-uz-Zaman SM, Shameel S, Perveen S, Ali Z "Steroidal saponins from Asparagus dumosus" - Phytochemistry 50(3) (1998) 481-484
  

  A new steroidal saponin, dumoside, characterized as (20S)-3β,16β- dihydroxy pregn-5-ene-22-carboxylic acid (22,16)-lactone-3-O-β- chacotrioside, was isolated from the whole plant of Asparagus dumosus Baker and the structure was deduced from spectral data. In addition to dumoside three more steroidal saponins characterized as 3β-dihydroxy pregn-5,16- dien-20-one 3-O-β-chacotrioside, 3β,22α,26-trihydroxyfurost-5-ene-3-O-β- chacotrioside-26-O-β-D-glucopyranoside and its corresponding 22α-O methoxy analogue were also isolated for the first time from this source. The structures have been identified with the help of FAB-MS, 1H NMR, 13C NMR and extensive 2D NMR spectroscopy, as well as comparison with reported spectroscopic data.

  glycoside, steroidal saponins, Liliaceae, whole plant, Asparagus dumosus, Dumoside

  Publication DOI: 10.1016/S0031-9422(98)00566-4
  Journal NLM ID: 0151434
  Publisher: Elsevier
  Institutions: H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan
  Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, acid hydrolysis, HPLC, extraction, optical rotation measurement, HMBC, HETEROCOSY, melting poind determination
  
   
  
  Asparagus dumosus
  CSDB ID 63504 (all data & tools)
• Article ID: 11947
  Ahmad VU, Khaliq-uz-Zaman SM, Shameel S, Perveen S, Ali Z "Steroidal saponins from Asparagus dumosus" - Phytochemistry 50(3) (1999) 481-484
  

  A new steroidal saponin, dumoside, characterized as (20S)-3β,16β-dihydroxy pregn-5-ene-22-carboxylic acid (22,16)-lactone-3-O-β-chacotrioside, was isolated from the whole plant of Asparagus dumosus Baker and the structure was deduced from spectral data. In addition to dumoside three more steroidal saponins characterized as 3β-dihydroxy pregn-5,16-dien-20-one 3-O-β-chacotrioside, 3β,22α,26-trihydroxyfurost-5-ene-3-O-β-chacotrioside-26-O-β-D-glucopyranoside and its corresponding 22α-O methoxy analogue were also isolated for the first time from this source. The structures have been identified with the help of FAB-MS, 1H NMR, 13C NMR and extensive 2D NMR spectroscopy, as well as comparison with reported spectroscopic data.

  glycoside, steroidal saponins, Liliaceae, whole plant, Asparagus dumosus, Dumoside

  NCBI PubMed ID: 9933956
  Publication DOI: 10.1016/S0031-9422(98)00566-4
  Journal NLM ID: 0151434
  Publisher: Elsevier
  Institutions: H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan
  Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, HPLC, HMBC, COSY, HCl hydrolysis
  
   
  
  Asparagus dumosus
  CSDB ID 64108 (all data & tools)

Show legend Show as text

Structure type: oligomer
Compound class: saponin glycoside, triterpenoid glycoside
Contained glycoepitopes: IEDB_136105,IEDB_142488,IEDB_146664,IEDB_225177,IEDB_885823,IEDB_983931,SB_192

• Article ID: 11534
  Ahmad VU, Khaliq-uz-Zaman SM, Shameel S, Perveen S, Ali Z "Steroidal saponins from Asparagus dumosus" - Phytochemistry 50(3) (1998) 481-484
  

  A new steroidal saponin, dumoside, characterized as (20S)-3β,16β- dihydroxy pregn-5-ene-22-carboxylic acid (22,16)-lactone-3-O-β- chacotrioside, was isolated from the whole plant of Asparagus dumosus Baker and the structure was deduced from spectral data. In addition to dumoside three more steroidal saponins characterized as 3β-dihydroxy pregn-5,16- dien-20-one 3-O-β-chacotrioside, 3β,22α,26-trihydroxyfurost-5-ene-3-O-β- chacotrioside-26-O-β-D-glucopyranoside and its corresponding 22α-O methoxy analogue were also isolated for the first time from this source. The structures have been identified with the help of FAB-MS, 1H NMR, 13C NMR and extensive 2D NMR spectroscopy, as well as comparison with reported spectroscopic data.

  glycoside, steroidal saponins, Liliaceae, whole plant, Asparagus dumosus, Dumoside

  Publication DOI: 10.1016/S0031-9422(98)00566-4
  Journal NLM ID: 0151434
  Publisher: Elsevier
  Institutions: H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan
  Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, acid hydrolysis, HPLC, extraction, optical rotation measurement, HMBC, HETEROCOSY, melting poind determination
  
   
  
  Asparagus dumosus
  CSDB ID 63505 (all data & tools)
• Article ID: 11947
  Ahmad VU, Khaliq-uz-Zaman SM, Shameel S, Perveen S, Ali Z "Steroidal saponins from Asparagus dumosus" - Phytochemistry 50(3) (1999) 481-484
  

  A new steroidal saponin, dumoside, characterized as (20S)-3β,16β-dihydroxy pregn-5-ene-22-carboxylic acid (22,16)-lactone-3-O-β-chacotrioside, was isolated from the whole plant of Asparagus dumosus Baker and the structure was deduced from spectral data. In addition to dumoside three more steroidal saponins characterized as 3β-dihydroxy pregn-5,16-dien-20-one 3-O-β-chacotrioside, 3β,22α,26-trihydroxyfurost-5-ene-3-O-β-chacotrioside-26-O-β-D-glucopyranoside and its corresponding 22α-O methoxy analogue were also isolated for the first time from this source. The structures have been identified with the help of FAB-MS, 1H NMR, 13C NMR and extensive 2D NMR spectroscopy, as well as comparison with reported spectroscopic data.

  glycoside, steroidal saponins, Liliaceae, whole plant, Asparagus dumosus, Dumoside

  NCBI PubMed ID: 9933956
  Publication DOI: 10.1016/S0031-9422(98)00566-4
  Journal NLM ID: 0151434
  Publisher: Elsevier
  Institutions: H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan
  Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, HPLC, HMBC, COSY, HCl hydrolysis
  
   
  
  Asparagus dumosus
  CSDB ID 64109 (all data & tools)