Three new alkaloids were isolated from the root-wood of Brucea mollis var. tonkinensis collected in China. Their structures were determined to be 11-O-β-d-glucopyranosyl-(1→6)-β-d-glucopyranosylcanthin-6-one, 5-O-β-d-glucopyranosyl-(1→6)-β-d-glucopyranosylcanthin-6-one and 11-hydroxycanthin-6-one-N-oxide, by chemical and spectral methods. In addition, two known alkaloids, canthin-6-one and canthin-6-one-N-oxide, were isolated.
canthin-6-one alkaloids, Brucea mollis var. tonkinensis, Simaroubaceae, root-wood
NCBI PubMed ID: 7765437Publication DOI: 10.1016/S0031-9422(00)89758-7Journal NLM ID: 0151434Publisher: Elsevier
Institutions: School of Pharmaceutical Sciences, Toho University, Chiba, Japan
Methods: 13C NMR, 1H NMR, EI-MS, gel filtration, FAB-MS, TLC, acid hydrolysis, UV, MPLC
Found